GKAP1 and SH3BP4

Data Source:
BioGRID (two hybrid)

		GKAP1	SH3BP4
Description		G kinase anchoring protein 1	SH3 domain binding protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus	Nucleus Cytoplasm Clathrin-coated Pit Clathrin-coated Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	GDP-dissociation Inhibitor Activity Protein Binding Small GTPase Binding Identical Protein Binding
	Biological Process	Signal Transduction Positive Regulation Of Insulin Receptor Signaling Pathway	Endocytosis Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways			Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Chronotype ( 30696823) Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Triglyceride levels ( 32154731)	Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		22 interacting genes: AP3B1 C1orf35 DHFR FAM124B FXR2 HDDC3 HGS HSD11B1 KANK2 KAT5 L3MBTL2 MFAP1 NDN PHOSPHO2 PRKG1 RCOR3 SDCBP SH3BP4 SOX18 UBQLN1 UBQLN4 ZCCHC10	22 interacting genes: C2orf73 CCT3 CEP78 CIZ1 DNAJA4 FKBP4 GAPDHS GIPC1 GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 TCP1 TTC1 TXNL1 YWHAE YWHAG ZBTB37
Entrez ID		80318	23677
HPRD ID		17042	09285
Ensembl ID		ENSG00000165113	ENSG00000130147
Uniprot IDs		Q5VSY0	Q9P0V3
PDB IDs
Enriched GO Terms of Interacting Partners?
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