EFHC2 and FBXL19

Data Source:
BioGRID (two hybrid)

		EFHC2	FBXL19
Description		EF-hand domain containing 2	F-box and leucine rich repeat protein 19
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GO Annotations	Cellular Component	Microtubule Axoneme Ciliary Basal Body Mitotic Spindle	Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Calcium Ion Binding Protein Binding Alpha-tubulin Binding	Transcription Coregulator Activity Protein Binding Zinc Ion Binding Histone Demethylase Activity Unmethylated CpG Binding
	Biological Process	Mitotic Cytokinesis Mitotic Spindle Organization Regulation Of Neuron Projection Development Cilium-dependent Cell Motility Cellular Response To Leukemia Inhibitory Factor	Protein Polyubiquitination Regulation Of Transcription By RNA Polymerase II Protein Demethylation Histone Demethylation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Mean arterial pressure ( 29403010)	Diastolic blood pressure ( 28135244 27841878) Mean corpuscular volume ( 27863252) Psoriasis ( 25903422 20953189 25574825 23143594) Psoriasis vulgaris ( 26626624) Psoriatic arthritis ( 26626624) Pulse pressure ( 27841878)
Interacting Genes		100 interacting genes: AASDHPPT ARHGEF5 ARMC7 CABP2 CACNB4 CARD9 CCDC102B CCDC120 CCDC13 CCDC57 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CPNE2 CPNE7 CYFIP1 DCLK1 DDX6 DGCR6 DRC7 EDC3 EFHC1 EGLN3 EMD ENKD1 ESRRG EXOC8 EXOSC5 FAM107A FAM124B FAM214B FAM221B FBXL19 GEM GLYCTK GOLGA1 GPKOW GRB2 GYS1 HDAC4 HGS HNRNPLL INPP5J JAKMIP2 KANK2 KCTD7 KIF9 L3MBTL2 LMNB2 LMO2 LNX1 LONRF1 MAGOHB MAPK9 MID2 MISP MYLIP MYO5B NCDN NCK2 NDOR1 NEK6 NFKBID NME7 NR3C1 PBLD PHF1 PIBF1 PICK1 PLOD3 POLR1C PRPF18 PTK6 QARS1 RAD51D RCOR3 RECK RHOBTB3 RUNX1T1 SNRNP25 SOGA1 SPATA18 SPG21 STK16 TBC1D1 TBC1D22B TEKT4 TRIM42 TRIM50 TSSK3 TUBGCP4 TXK U2AF1 U2AF1L5 USP2 ZBTB16 ZFHX3 ZZZ3	13 interacting genes: ABI1 ABI2 CBFA2T2 CREBBP DGAT2L6 EFHC2 NCK2 PSME3 RPRM SORBS3 TMEM239 TRIM27 TRIM29
Entrez ID		80258	54620
HPRD ID		06540	12366
Ensembl ID		ENSG00000183690	ENSG00000099364
Uniprot IDs		Q5JST6	H3BVB1 Q6PCT2
PDB IDs		2Z13 2Z14	6ASB
Enriched GO Terms of Interacting Partners?
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