THOC7 and CCDC146

  • Data Source:
  • BioGRID (two hybrid)

THOC7

CCDC146

Description THO complex 7 coiled-coil domain containing 146
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Cortical surface area (MOSTest) ( 32665545)
  • Neutrophil count ( 32888494)
  • Refractive error ( 32231278)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • White blood cell count ( 32888494)
Interacting Genes 11 interacting genes: CCDC146 CHD3 CKAP4 GOT2 MED22 MED8 MNS1 NDC80 NIF3L1 SMARCD1 THOC5 71 interacting genes: AKAP9 BLOC1S2 CBY2 CCDC136 CCDC197 CCNDBP1 CDR2 CDR2L CENPH CEP170P1 CEP44 DTNBP1 FSD2 GAS8 GMNN GOLGA2 GOLGA6L9 GPRASP2 GRAMD4 HSF2BP INSYN1 KIFC3 KRT16 KRT18 KRT19 KRT24 KRT26 KRT27 KRT31 KRT34 KRT38 KRT40 KRT86 LHX3 MAGEA11 MAGEA6 MCC MED4 MIPOL1 MRFAP1 MTUS2 N4BP3 NAP1L2 NECAB2 NINL NUP62 PDE4DIP PLEKHF2 PNMA1 PPP2R3C PROSER3 PSMC6 RINT1 RNF40 RPGRIP1 SH3BP1 SYCE1L TEPSIN TFIP11 THOC7 TNR TPM3 TRAF1 TRIM23 TRIM54 TRIML2 TSC22D4 TXLNA USHBP1 VPS28 VPS52
Entrez ID 80145 57639
HPRD ID 17632 11150
Ensembl ID ENSG00000163634 ENSG00000135205
Uniprot IDs A0A024R332 A0A5S6STF9 Q6I9Y2 Q8IYE0 Q96MS1
PDB IDs
Enriched GO Terms of Interacting Partners?
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