MINDY3 and RPL8

Data Source:
HPRD (two hybrid)

		MINDY3	RPL8
Description		MINDY lysine 48 deubiquitinase 3	ribosomal protein L8
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nuclear Membrane	Cytosol Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome Postsynapse
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Lys48-specific Deubiquitinase Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding 5.8S RRNA Binding
	Biological Process	Apoptotic Process Protein Phosphopantetheinylation Protein K48-linked Deubiquitination	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Cellular Response To Nerve Growth Factor Stimulus
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			(S)-3-phenyllactic acid Anisomycin Puromycin
Diseases
GWAS			Blood metabolite levels ( 26401656) Logical memory (immediate recall) in normal cognition ( 29274321)
Interacting Genes		9 interacting genes: DAZAP2 MAP3K1 RAD23A RPL8 SDCBP SMURF1 TRIM49 TRIM49C UBC	14 interacting genes: ARIH2 ARL15 C11orf49 CHDH DPH3 DUSP23 DUX4 FGFR3 IL7R MINDY3 NUDT3 ST3GAL3 UBE2I UPF2
Entrez ID		80013	6132
HPRD ID		10702	16044
Ensembl ID		ENSG00000148481	ENSG00000161016
Uniprot IDs		Q9H8M7	P62917
PDB IDs			4CCM 4CCN 4CCO 4UG0 4V6X 4Y3O 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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