RPL8 and MINDY3

Data Source:
HPRD (two hybrid)

		RPL8	MINDY3
Description		ribosomal protein L8	MINDY lysine 48 deubiquitinase 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome Postsynapse	Nucleoplasm Nuclear Membrane
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding 5.8S RRNA Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Lys48-specific Deubiquitinase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Cellular Response To Nerve Growth Factor Stimulus	Apoptotic Process Protein Phosphopantetheinylation Protein K48-linked Deubiquitination
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		(S)-3-phenyllactic acid Anisomycin Puromycin
Diseases
GWAS		Blood metabolite levels ( 26401656) Logical memory (immediate recall) in normal cognition ( 29274321)
Interacting Genes		14 interacting genes: ARIH2 ARL15 C11orf49 CHDH DPH3 DUSP23 DUX4 FGFR3 IL7R MINDY3 NUDT3 ST3GAL3 UBE2I UPF2	9 interacting genes: DAZAP2 MAP3K1 RAD23A RPL8 SDCBP SMURF1 TRIM49 TRIM49C UBC
Entrez ID		6132	80013
HPRD ID		16044	10702
Ensembl ID		ENSG00000161016	ENSG00000148481
Uniprot IDs		P62917	Q9H8M7
PDB IDs		4CCM 4CCN 4CCO 4UG0 4V6X 4Y3O 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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