PIP4K2C and INHBE

Data Source:
BioGRID (two hybrid, two hybrid)

		PIP4K2C	INHBE
Description		phosphatidylinositol-5-phosphate 4-kinase type 2 gamma	inhibin subunit beta E
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Autophagosome Endoplasmic Reticulum Cytosol Plasma Membrane Intracellular Organelle Extracellular Exosome	Extracellular Space Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-phosphate 4-kinase Activity Identical Protein Binding	Cytokine Activity Hormone Activity Growth Factor Activity
	Biological Process	Phosphatidylinositol Biosynthetic Process Regulation Of Autophagy Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol Phosphorylation Negative Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Biosynthetic Process Positive Regulation Of Autophagosome Assembly	Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction
Pathways		Synthesis of PIPs at the plasma membrane PI5P Regulates TP53 Acetylation PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Synthesis of PIPs in the nucleus	Glycoprotein hormones
Drugs		Fostamatinib
Diseases
GWAS		Rheumatoid arthritis ( 18794853)	HDL cholesterol ( 30275531) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Red cell distribution width ( 32888494) Urate levels ( 23263486)
Interacting Genes		4 interacting genes: APP BTK FBXO25 PJA1	1 interacting genes: FST
Entrez ID		79837	83729
HPRD ID		15138	11047
Ensembl ID		ENSG00000166908	ENSG00000139269
Uniprot IDs		B3KQV3 Q8TBX8	P58166
PDB IDs		2GK9
Enriched GO Terms of Interacting Partners?
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