KDM8 and IFT20

Data Source:
BioGRID (two hybrid)

		KDM8	IFT20
Description		lysine demethylase 8	intraflagellar transport 20
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytosol	Golgi Membrane Photoreceptor Outer Segment Golgi Apparatus Cis-Golgi Network Centrosome Centriole Microvillus Cilium Intraciliary Transport Particle B Motile Cilium Photoreceptor Connecting Cilium Stereocilium Dendrite Terminus Ciliary Tip Ciliary Base Kinociliary Basal Body
	Molecular Function	Chromatin Binding Endopeptidase Activity Aminopeptidase Activity Protein Binding 2-oxoglutarate-dependent Dioxygenase Activity Methylated Histone Binding Metal Ion Binding Histone Demethylase Activity (H3-K36 Specific) L-arginine 3-hydroxylase Activity	Opsin Binding Protein Binding Small GTPase Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Proteolysis Protein Destabilization Circadian Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Histone H3-K36 Demethylation	Establishment Of Planar Polarity Kidney Development Smoothened Signaling Pathway Spermatogenesis Visual Learning Protein Localization To Golgi Apparatus Intraciliary Transport Involved In Cilium Assembly Photoreceptor Cell Outer Segment Organization Opsin Transport Intraciliary Transport Establishment Of Epithelial Cell Apical/basal Polarity Centrosome Localization Cardiac Muscle Cell Differentiation Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Canonical Wnt Signaling Pathway Neural Precursor Cell Proliferation Protein Localization To Cilium Protein Localization To Plasma Membrane Cochlea Development Regulation Of Cilium Assembly Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Regulation Of Autophagosome Assembly
Pathways			Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Asthma ( 31959851 31619474) Gut microbiota (bacterial taxa) ( 27723756) Night sleep phenotypes ( 27126917)	Osteoprotegerin levels ( 25080503)
Interacting Genes		6 interacting genes: DDIT4L IFT20 ISY1 MEOX2 NUBPL PCYT2	46 interacting genes: ABI2 ABI3 AQP1 BLOC1S6 C1orf216 CCHCR1 CD209 CLEC4M CORO1A CROCCP2 DISC1 DTNBP1 EMILIN1 EXOC7 FAM81B FBF1 FSD2 GOLGA2 HAUS1 HTT IFT57 KAT5 KDM8 KIF3B KNSTRN KPNA2 KRT13 KXD1 MED30 MIS18A NDC80 NUP54 NUP62 OXNAD1 PBX4 PPP1R11 PSMA1 PTPN12 RASSF4 SH3BP5 SYCE2 TREX1 USHBP1 WASF1 WASHC3 ZDHHC17
Entrez ID		79831	90410
HPRD ID		07836	17137
Ensembl ID		ENSG00000155666	ENSG00000109083
Uniprot IDs		A0A0S2Z5P8 A0A0S2Z5T1 Q8N371	A0A024QZ08 A0A087X2B4 Q8IY31
PDB IDs		3UYJ 4AAP 4GAZ 4GJY 4GJZ 4QU1 5FBJ 6AVS 6AX3 6F4M 6F4N 6F4O 6F4P 6F4Q 6F4R 6F4S 6F4T 6I9L 6I9M 6I9N
Enriched GO Terms of Interacting Partners?
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