GEMIN7 and SNRPE

Data Source:
HPRD (in vitro)

		GEMIN7	SNRPE
Description		gem nuclear organelle associated protein 7	small nuclear ribonucleoprotein polypeptide E
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies Sm-like Protein Family Complex	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Telomerase Holoenzyme Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding	RNA Binding Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Import Into Nucleus	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process Hair Cycle Import Into Nucleus
Pathways		snRNP Assembly	SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cerebrospinal fluid AB1-42 levels ( 28247064)	Male-pattern baldness ( 28196072) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		20 interacting genes: ADD1 CEP126 EDRF1 FEZ1 GEMIN6 GOLM1 KAT5 RN7SL1 RNU1-1 RNU2-1 RPLP1 SHC1 SMN1 SNRPB SNRPD2 SNRPD3 SNRPE STRAP TAOK1 TUBA1A	18 interacting genes: DDX20 GEMIN5 GEMIN6 GEMIN7 HRAS IL7R LSM2 LSM3 LSM4 LSM5 SMN1 SMN2 SNRPD3 SNRPF SNRPG STRAP WDR77 YWHAQ
Entrez ID		79760	6635
HPRD ID		07600	00548
Ensembl ID		ENSG00000142252	ENSG00000182004
Uniprot IDs		Q9H840	P62304
PDB IDs		1Y96	3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6V4X 6Y53 6Y5Q 7A5P
Enriched GO Terms of Interacting Partners?
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