SNIP1 and PHF19

Data Source:
BioGRID (two hybrid)

		SNIP1	PHF19
Description		Smad nuclear interacting protein 1	PHD finger protein 19
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol U2-type Precatalytic Spliceosome	Nucleus Nucleoplasm ESC/E(Z) Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding	DNA Binding Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II I-kappaB Kinase/NF-kappaB Signaling Production Of MiRNAs Involved In Gene Silencing By MiRNA	Chromatin Organization Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Histone H3-K27 Methylation
Pathways			PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Axial length ( 24144296) Eyebrow thickness ( 26926045)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Birth weight ( 31043758 27680694) Corneal astigmatism ( 29422769) High density lipoprotein cholesterol levels ( 29403010) Prostate-specific antigen levels ( 28139693) Pulse pressure ( 28135244 27618448) Refractive error ( 32231278)
Interacting Genes		49 interacting genes: CDK6 CLK2 CLK3 CREBBP DVL2 DVL3 EIF3C EP300 ESRRG FAF1 GMEB1 GYS1 HIPK1 HIPK3 KRTAP10-6 MAX MYC PHF19 PIAS1 PIAS2 PIAS3 PIAS4 POU2F1 PRPF3 PRPF40A RELA SETDB1 SF3B1 SMAD1 SMAD2 SMAD4 SON SP100 SPANXN2 SRPK2 SRRM4 STK3 TDG TNIP1 TOPORS TSPYL2 TTC14 UBE2I ZBTB9 ZCCHC10 ZCCHC7 ZMYM2 ZMYM5 ZNF451	21 interacting genes: BAG4 CSNK2A1 DVL3 H3C1 HOMEZ HOXB5 INO80E KDM1A LZTS2 PICK1 POTEB3 RCOR3 SNIP1 SUV39H1 SUV39H2 THAP1 THAP7 TSPYL2 YTHDC1 ZNF837 ZRANB1
Entrez ID		79753	26147
HPRD ID		06999	17846
Ensembl ID		ENSG00000163877	ENSG00000119403
Uniprot IDs		B1AK66 Q8TAD8	A0A087X169 B7Z887 B7Z8H3 F5H8K3 Q5T6S3
PDB IDs		5Z56 5Z57 5Z58 6FF7	2E5Q 4BD3 6NQ3 6WAU
Enriched GO Terms of Interacting Partners?
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