BBS10 and FRZB

Data Source:
BioGRID (two hybrid)

		BBS10	FRZB
Description		Bardet-Biedl syndrome 10	frizzled related protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium	Extracellular Space Cytoplasm Membrane
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding ATP Binding	Protein Binding Wnt-protein Binding
	Biological Process	Visual Perception Regulation Of Protein-containing Complex Assembly Photoreceptor Cell Maintenance Response To Stimulus Chaperone-mediated Protein Complex Assembly Non-motile Cilium Assembly	Skeletal System Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Development Neural Crest Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Non-canonical Wnt Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Fat Cell Differentiation Convergent Extension Involved In Organogenesis Canonical Wnt Signaling Pathway Negative Regulation Of Cartilage Development Somite Development Negative Regulation Of Hepatocyte Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Cochlea Morphogenesis
Pathways		BBSome-mediated cargo-targeting to cilium
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS			Blood protein levels ( 30072576 29875488 28240269) Heel bone mineral density ( 30598549 28869591) Neurological blood protein biomarker levels ( 31320639) Night sleep phenotypes ( 27126917) Waist-to-hip circumference ratio (dietary energy interaction) ( 23192594) Working memory ( 31598132)
Interacting Genes		12 interacting genes: CSNK1E FRZB HDAC6 MAP3K7 MAPK6 MAPK8IP2 NR4A1 PTK2 RASA1 RGS2 TNFSF11 YAE1	8 interacting genes: BBS10 CYSRT1 EHF ELF5 PNO1 POLA2 RBX1 SMAD1
Entrez ID		79738	2487
HPRD ID		08036	07282
Ensembl ID		ENSG00000179941	ENSG00000162998
Uniprot IDs		Q8TAM1	D9ZGF6 Q92765
PDB IDs
Enriched GO Terms of Interacting Partners?
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