PLEKHF2 and MAGI2

  • Data Source:
  • BioGRID (two hybrid)

PLEKHF2

MAGI2

Description pleckstrin homology and FYVE domain containing 2 membrane associated guanylate kinase, WW and PDZ domain containing 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 23007406)
  • Adult body size ( 32376654)
  • Adverse response to drug ( 30420678)
  • Airway wall thickness ( 25517131)
  • Bitter beverage consumption ( 31046077)
  • Body mass index ( 28892062 25673413)
  • Body size at age 10 ( 32376654)
  • Bronchopulmonary dysplasia ( 23897914)
  • Chronotype ( 30696823)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • General risk tolerance (MTAG) ( 30643258)
  • Hippocampal atrophy ( 19668339)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • LDL cholesterol levels x short total sleep time interaction (1df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Lead levels in blood ( 25820613)
  • Mammographic density (dense area) ( 25342443)
  • Memory dysfunction in frontotemporal lobe dementia ( 29724592)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Obesity-related traits ( 23251661)
  • Pursuit maintenance gain ( 29064472)
  • Refractive error ( 32231278)
  • Response to anti-depressant treatment in major depressive disorder ( 22041458)
  • Response to lamotrigine and valproic acid in genetic generalized epilepsy ( 32308125)
  • Schizophrenia ( 28991256 30285260)
  • Serum folate levels ( 29953918)
  • Visceral fat ( 30942860)
Interacting Genes 168 interacting genes: ABCG4 ACY3 ADAP1 AIDA AIMP2 ANO9 APP APPL1 ARID4B ARL14EP ASPH BARHL2 BCAS2 BCAS3 BEND7 BLOC1S6 BOD1 BRD7 BSCL2 C11orf45 C1orf35 C3 CAVIN2 CBX8 CCDC146 CCDC172 CCDC25 CCDC85B CDC20B CEP44 CERK CGGBP1 CHCHD2 CHIC2 COX5B CRYBA1 DAZAP2 DMRT3 DNAAF11 DOCK2 DOCK3 DPPA4 DRAP1 DTX2 DUSP4 DUT EIF3C EML2 EXOC7 FAH FBXO28 FBXW5 FGF13 FHL3 FLNA FRMD8 GAGE12G GAGE2E GEM GFER GLUL GNMT GPBP1 GPBP1L1 GRAMD4 GTPBP2 HEBP2 HSPB7 INO80 KCNAB3 KRTAP10-10 KRTAP5-4 L3MBTL3 LDOC1 MAGI2 MAP2K1 MAX MBIP MBP MEAF6 MFAP1 MIDN MPP4 MRI1 NDUFA5 NFIA NONO NPM2 NSD2 NUDT2 NUTM1 P2RX7 PACSIN1 PAK1IP1 PDK4 PIK3R3 PPCDC PPP1R18 PRDM14 PRKAG1 PRKAR1A PRPSAP1 PTPN3 PWWP2A RAB28 RABAC1 RADX RARA RASGEF1B RGS10 RGS8 RPAP2 RPE RPRM RPS21 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SAMD11 SCYL1 SEC14L4 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SNRNP35 SOST SPATA24 SPEF1 SPON2 STAMBPL1 SYT16 TBCEL TBX3 TCEANC THAP10 THG1L TNFAIP8 TNFAIP8L1 TP53BP2 TRAF6 TRAM1L1 TRAPPC3 TRIAP1 TRIM22 TSC22D3 TTC9C TXNL4B UBE2Z UGP2 USF1 XCR1 XRN2 YIF1A YY1 ZBTB6 ZDHHC24 ZFYVE26 ZNF165 ZNF250 ZNF263 ZNF398 ZNF439 ZNF581 24 interacting genes: ACVR2A ADGRB1 ADRB1 ARRDC3 ATN1 CRHR1 CTNNB1 CTNND2 DLGAP1 DLGAP2 DLGAP3 DLL1 DSCAML1 GRID2 MORN4 PDZD11 PLEKHF2 PLXNB3 PTEN RAPGEF2 RPS6KA1 SMAD3 SNRPB TGFA
Entrez ID 79666 9863
HPRD ID 15147 16212
Ensembl ID ENSG00000175895 ENSG00000187391
Uniprot IDs Q9H8W4 B7Z4H4 Q86UL8
PDB IDs 1UEP 1UEQ 1UEW 1UJV 1WFV
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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