CORO7 and TOB1

Data Source:
BioGRID (enzymatic study)

		CORO7	TOB1
Description		coronin 7	transducer of ERBB2, 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Integral Component Of Membrane Cytoplasmic Vesicle	Nucleus Cytoplasm CCR4-NOT Complex
	Molecular Function	Actin Binding Protein Binding Actin Filament Binding	Transcription Corepressor Activity Protein Binding Receptor Tyrosine Kinase Binding SMAD Binding
	Biological Process	Golgi To Endosome Transport Actin Filament Organization Protein Transport Actin Filament Polymerization	Negative Regulation Of Cell Population Proliferation Regulation Of Gene Expression Negative Regulation Of Translation Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Pathways
Drugs
Diseases
GWAS		Eosinophil counts ( 32888494) Erectile dysfunction ( 30583798) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 25673412) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Schizophrenia ( 28991256) Waist-to-hip ratio adjusted for BMI ( 30389748) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Blood protein levels ( 28240269)
Interacting Genes		9 interacting genes: ACTB AP1M1 AP2M1 EPS15 KLHL20 SRC TOB1 WASL ZRANB1	19 interacting genes: APP CDC7 CNOT7 CORO7 DTL ERBB2 MAPK1 MAPK9 MARCKS PABPC1 SCMH1 SETDB1 SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD6 SMAD9
Entrez ID		79585	10140
HPRD ID		07975	09273
Ensembl ID		ENSG00000262246	ENSG00000141232
Uniprot IDs		P57737	P50616
PDB IDs			2D5R 2Z15 5CI8 5CI9
Enriched GO Terms of Interacting Partners?
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