GCC1 and PPP1R27

Data Source:
BioGRID (two hybrid)

		GCC1	PPP1R27
Description		GRIP and coiled-coil domain containing 1	protein phosphatase 1 regulatory subunit 27
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Trans Cisterna Golgi Membrane Golgi Apparatus Cytosol
	Molecular Function	Protein Binding Small GTPase Binding	Protein Phosphatase Inhibitor Activity Protein Binding Phosphatase Binding
	Biological Process		Negative Regulation Of Phosphatase Activity Negative Regulation Of Phosphoprotein Phosphatase Activity
Pathways		Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Feeling worry ( 29500382) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Medication adherence in chronic diseases ( 25317111) Refractive error ( 32231278) Type 2 diabetes ( 26818947 22158537 30718926)
Interacting Genes		64 interacting genes: ABI2 AMOTL2 APP ARL1 ATF4 ATN1 BIRC2 BRCA1 C1orf94 CCDC33 CCDC85B CEP57 CEP70 COIL CPSF7 DISC1 DNAJA3 FAM83A FBF1 FBXO28 FIGNL1 FOSL1 GAS8 GLI1 GOLGA2 GTF2I HDX ICA1L IKBKG ITSN1 KATNAL1 KDM1A KIAA0753 KIAA1217 KIF5B LCA5 LZTS2 MCRS1 MED4 MEOX1 MID2 NAB2 NAV1 NECAB2 NINL OIP5 PAK5 PPP1R18 PPP1R27 PRPF18 RUNX1 SMARCD1 SPOP TFIP11 TLE5 TP53BP2 TRIM29 TRIM50 USHBP1 UTP14C XIAP ZC4H2 ZFP90 ZNF276	9 interacting genes: DDIT4L GCC1 KRT34 MVB12A NTAQ1 PPP1CA PPP1CB RPL9 SMCP
Entrez ID		79571	116729
HPRD ID		07599	17334
Ensembl ID		ENSG00000179562	ENSG00000182676
Uniprot IDs		A4D0Z4 Q96CN9	Q86WC6
PDB IDs
Enriched GO Terms of Interacting Partners?
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