WDR25 and FOXI1

Data Source:
BioGRID (two hybrid)

		WDR25	FOXI1
Description		WD repeat domain 25	forkhead box I1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Nucleolus Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity DNA Binding, Bending Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Embryo Development Ending In Birth Or Egg Hatching Cell Differentiation Inner Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases			Thyroid dyshormonogenesis; Dyshormogenetic goiter
GWAS		Menarche (age at onset) ( 27182965 25231870) Refractive error ( 32231278)	Acne (severe) ( 24927181) Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065)
Interacting Genes		31 interacting genes: AKAP8L C19orf54 CNFN CYSRT1 DVL3 FAM168B FHL3 FOXI1 GOLGA6L9 HSF2BP KRT31 KRT34 KRT40 KRTAP12-3 KRTAP15-1 KRTAP3-1 KRTAP6-3 LDOC1 LNX1 MKRN3 NBPF19 NOTCH2NLA NOTCH3 PFDN5 PNMA1 PRDM14 PSME3 TEPSIN TRIM23 UBXN11 ZNF34	26 interacting genes: ANKRD10 APP ARSA ATP23 BATF2 CSTF2T DTX2 FAM168B FAM83A HGS HSF4 JMJD7 KRTAP19-1 KRTAP19-7 MAGED1 MLLT10 NFKBID PIN1 RAMAC TEKT5 TENT5B UFSP1 USP54 VPS37C WDR25 WWOX
Entrez ID		79446	2299
HPRD ID		14649	03057
Ensembl ID		ENSG00000176473	ENSG00000168269
Uniprot IDs		A0A384NPW5 Q64LD2	E0XEN6 Q12951
PDB IDs
Enriched GO Terms of Interacting Partners?
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