CENPO and DRC1

Data Source:
BioGRID (affinity chromatography technology)

		CENPO	DRC1
Description		centromere protein O	dynein regulatory complex subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body Mis6-Sim4 Complex	Cytosol Axonemal Dynein Complex Axoneme Motile Cilium
	Molecular Function	Protein Binding
	Biological Process	CENP-A Containing Nucleosome Assembly	Regulation Of Cilium Movement Determination Of Left/right Symmetry Heart Development Cilium-dependent Cell Motility Axonemal Dynein Complex Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat mass ( 28552196) Body mass index ( 26426971 29273807) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cognitive function ( 28093568) Coronary artery disease ( 29212778) Height ( 28552196 25282103 23563607) Multiple sclerosis ( 24076602) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Trunk fat mass ( 28552196) Type 1 diabetes ( 21980299)
Interacting Genes		7 interacting genes: CENPP CEP170P1 DCDC2 ERI3 FOS FOSB NECAB2
Entrez ID		79172	92749
HPRD ID		14414	11312
Ensembl ID		ENSG00000138092	ENSG00000157856
Uniprot IDs		Q9BU64	Q96MC2
PDB IDs
Enriched GO Terms of Interacting Partners?
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