TAF1D and FAM20C

Data Source:
BioGRID (two hybrid)

		TAF1D	FAM20C
Description		TATA-box binding protein associated factor, RNA polymerase I subunit D	FAM20C golgi associated secretory pathway kinase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus Cytosol Centriolar Satellite Mitotic Spindle	Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Extracellular Exosome
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Phosphotransferase Activity, Alcohol Group As Acceptor Manganese Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Positive Regulation Of Gene Expression, Epigenetic	Protein Phosphorylation Biomineral Tissue Development Post-translational Protein Modification Cellular Protein Metabolic Process ATP Metabolic Process Enamel Mineralization Odontoblast Differentiation
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases			Raine syndrome; Lethal osteosclerotic bone dysplasia
GWAS			Allergic rhinitis ( 25085501) Alzheimer's disease in APOE e4- carriers ( 25778476)
Interacting Genes		24 interacting genes: CEP70 DDAH2 EZH2 FAF1 FAM20C FEZ1 HAP1 HSP90AB1 IMMT ING5 ITFG1 LRIF1 MCM3AP MCPH1 NGEF NHLH2 POLB PTN RPL36AL SMARCB1 TAF1B TMSB4X UBE2D1 UBTF	7 interacting genes: FAM118B PFDN1 SMN1 SUV39H2 TAF1D TK1 TSC22D1
Entrez ID		79101	56975
HPRD ID		14679	13298
Ensembl ID		ENSG00000166012	ENSG00000177706
Uniprot IDs		A0A024R3A9 Q9H5J8	Q8IXL6
PDB IDs			5YH3
Enriched GO Terms of Interacting Partners?
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