TMEM109 and SLC18A2

Data Source:
BioGRID (two hybrid)

		TMEM109	SLC18A2
Description		transmembrane protein 109	solute carrier family 18 member A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Outer Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Membrane Extracellular Exosome	Centrosome Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Synaptic Vesicle Membrane Terminal Bouton Intracellular Membrane-bounded Organelle Clathrin-sculpted Monoamine Transport Vesicle Membrane Dopaminergic Synapse
	Molecular Function	Molecular_function Voltage-gated Ion Channel Activity Protein Binding	Serotonin:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Cell Death Cellular Response To Gamma Radiation	Response To Amphetamine Chemical Synaptic Transmission Neurotransmitter Secretion Locomotory Behavior Response To Toxic Substance Post-embryonic Development Aminergic Neurotransmitter Loading Into Synaptic Vesicle Monoamine Transport Dopamine Transport Sequestering Of Neurotransmitter Serotonin Uptake Transmembrane Transport Neurotransmitter Loading Into Synaptic Vesicle Negative Regulation Of Reactive Oxygen Species Biosynthetic Process
Pathways			Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Na+/Cl- dependent neurotransmitter transporters
Drugs			Amphetamine Reserpine Norepinephrine Haloperidol Mazindol Benzphetamine Dopamine Deserpidine Ephedra sinica root MMDA Midomafetamine 4-Methoxyamphetamine Dextroamphetamine Metamfetamine Nomifensine Tetrabenazine Histamine Isometheptene Propylhexedrine Serotonin Rauwolfia serpentina root Deutetrabenazine
Diseases
GWAS			Body mass index ( 26426971) Retinopathy x type 2 diabetes interaction ( 32541925)
Interacting Genes		16 interacting genes: AQP2 AQP9 ERGIC3 GOLM1 GPX8 LMNA MGST3 MTIF3 PDZK1IP1 RNF170 SAR1A SLC18A2 SPINT1 STOM TMEM52B TMEM80	14 interacting genes: BRICD5 CFHR5 CMTM5 CSNK1A1 CSNK2A1 CSNK2A2 CXCR2 DNAJC5 GPR151 MFSD5 NKG7 SLC7A1 TMEM109 TOMM6
Entrez ID		79073	6571
HPRD ID		14687	01896
Ensembl ID		ENSG00000110108	ENSG00000165646
Uniprot IDs		Q9BVC6	Q05940
PDB IDs
Enriched GO Terms of Interacting Partners?
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