SLC18A2 and CFHR5

Data Source:
BioGRID (two hybrid)

		SLC18A2	CFHR5
Description		solute carrier family 18 member A2	complement factor H related 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Synaptic Vesicle Membrane Terminal Bouton Intracellular Membrane-bounded Organelle Clathrin-sculpted Monoamine Transport Vesicle Membrane Dopaminergic Synapse	Extracellular Region Protein-containing Complex
	Molecular Function	Serotonin:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Transmembrane Transporter Activity	Protein Binding Identical Protein Binding Protein Heterodimerization Activity
	Biological Process	Response To Amphetamine Chemical Synaptic Transmission Neurotransmitter Secretion Locomotory Behavior Response To Toxic Substance Post-embryonic Development Aminergic Neurotransmitter Loading Into Synaptic Vesicle Monoamine Transport Dopamine Transport Sequestering Of Neurotransmitter Serotonin Uptake Transmembrane Transport Neurotransmitter Loading Into Synaptic Vesicle Negative Regulation Of Reactive Oxygen Species Biosynthetic Process	Complement Activation, Alternative Pathway Regulation Of Complement Activation Negative Regulation Of Protein Binding Cytolysis By Host Of Symbiont Cells
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Na+/Cl- dependent neurotransmitter transporters	Regulation of Complement cascade
Drugs		Amphetamine Reserpine Norepinephrine Haloperidol Mazindol Benzphetamine Dopamine Deserpidine Ephedra sinica root MMDA Midomafetamine 4-Methoxyamphetamine Dextroamphetamine Metamfetamine Nomifensine Tetrabenazine Histamine Isometheptene Propylhexedrine Serotonin Rauwolfia serpentina root Deutetrabenazine
Diseases
GWAS		Body mass index ( 26426971) Retinopathy x type 2 diabetes interaction ( 32541925)	Age-related macular degeneration ( 23577725 23536807) Age-related macular degeneration (extreme sampling) ( 23577725) Age-related macular degeneration (MTAG) ( 32277175) Asthma ( 29273806) Blood protein levels ( 29875488 28240269) Lupus nephritis in systemic lupus erythematosus ( 24925725) Matrix metalloproteinase-8 levels ( 29212897) Nephropathy ( 21399633)
Interacting Genes		14 interacting genes: BRICD5 CFHR5 CMTM5 CSNK1A1 CSNK2A1 CSNK2A2 CXCR2 DNAJC5 GPR151 MFSD5 NKG7 SLC7A1 TMEM109 TOMM6	20 interacting genes: ARL13B C3 CISD2 CREB3 CREB3L1 EBAG9 ERGIC3 FFAR2 GPX8 KCNK7 LMNA MFSD14B PANX1 SLC10A1 SLC18A2 SLC4A1 STOM TMEM14B TMEM237 TMPRSS2
Entrez ID		6571	81494
HPRD ID		01896	06508
Ensembl ID		ENSG00000165646	ENSG00000134389
Uniprot IDs		Q05940	Q9BXR6
PDB IDs
Enriched GO Terms of Interacting Partners?
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