AHNAK and S100B

Data Source:
HPRD (in vitro, in vivo)

		AHNAK	S100B
Description		AHNAK nucleoprotein	S100 calcium binding protein B
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Lysosomal Membrane Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Membrane T-tubule Vesicle Sarcolemma Costamere Cell-cell Contact Zone Membrane Raft Extracellular Exosome	Ruffle Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding S100 Protein Binding Cadherin Binding Structural Molecule Activity Conferring Elasticity	Calcium Ion Binding Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Tau Protein Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Regulation Of RNA Splicing Regulation Of Voltage-gated Calcium Channel Activity	Axonogenesis Central Nervous System Development Learning Or Memory Positive Regulation Of Cell Population Proliferation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response
Pathways			Nuclear signaling by ERBB4 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling TRAF6 mediated NF-kB activation
Drugs			Olopatadine Calcium N-Formylmethionine Arundic acid (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide 2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Alzheimer's disease (late onset) ( 28714976) Blond vs. brown/black hair color ( 30531825) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cutaneous melanoma or hair colour ( 32341527) Gamma glutamyl transferase levels ( 29403010) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549 28869591) Lung function (FEV1) ( 28166213) Monocyte percentage of white cells ( 32888494) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Serum alkaline phosphatase levels ( 31666285) Triglyceride levels ( 32203549) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Lymphocyte counts ( 22286170)
Interacting Genes		10 interacting genes: AKT1 CDKN2A EGFR KLHL40 MEOX2 NOL9 POT1 S100B SUMO2 XRCC4	46 interacting genes: ADTRP AGER AGTRAP AHNAK ANXA6 BCL2L2 CACYBP CALM1 CAPZA1 CEP20 CT45A5 DES DNAJC30 FBXO7 FBXW5 GFAP GUCY2D IMP4 IMPA1 IQGAP1 LNX1 MAL2 MAPT MDM2 MDM4 NDRG1 NKAPD1 PGM1 RABAC1 S100A1 S100A11 S100A2 S100A4 S100A6 S100A9 S100P S100Z SDCBP SPG21 STK38 SUGT1 TMEM159 TMEM239 TNIP1 TP53 VAV1
Entrez ID		79026	6285
HPRD ID		14684	01505
Ensembl ID		ENSG00000124942	ENSG00000160307
Uniprot IDs		B4DTV0 Q09666 Q9BVU3	A0A0S2Z4C5 P04271
PDB IDs		4DRW 4FTG 4HRG	1MQ1 1UWO 2H61 2M49 2PRU 3CZT 3D0Y 3D10 3HCM 4XYN 5CSF 5CSI 5CSJ 5CSN 5D7F
Enriched GO Terms of Interacting Partners?
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