S100B and S100A11

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, two hybrid)

		S100B	S100A11
Description		S100 calcium binding protein B	S100 calcium binding protein A11
Image
GO Annotations	Cellular Component	Ruffle Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Ruffle Extracellular Region Extracellular Space Nucleus Cytoplasm Adherens Junction Secretory Granule Lumen Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Tau Protein Binding Calcium-dependent Protein Binding RAGE Receptor Binding	Calcium Ion Binding Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Axonogenesis Central Nervous System Development Learning Or Memory Positive Regulation Of Cell Population Proliferation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response	Signal Transduction Negative Regulation Of DNA Replication Negative Regulation Of Cell Population Proliferation Positive Regulation Of Smooth Muscle Cell Migration Neutrophil Degranulation Cell-cell Adhesion
Pathways		Nuclear signaling by ERBB4 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling TRAF6 mediated NF-kB activation	Neutrophil degranulation
Drugs		Olopatadine Calcium N-Formylmethionine Arundic acid (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide 2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide Calcium citrate Calcium Phosphate Calcium phosphate dihydrate	Phosphonothreonine
Diseases
GWAS		Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Lymphocyte counts ( 22286170)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 30929738 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Male-pattern baldness ( 28196072)
Interacting Genes		46 interacting genes: ADTRP AGER AGTRAP AHNAK ANXA6 BCL2L2 CACYBP CALM1 CAPZA1 CEP20 CT45A5 DES DNAJC30 FBXO7 FBXW5 GFAP GUCY2D IMP4 IMPA1 IQGAP1 LNX1 MAL2 MAPT MDM2 MDM4 NDRG1 NKAPD1 PGM1 RABAC1 S100A1 S100A11 S100A2 S100A4 S100A6 S100A9 S100P S100Z SDCBP SPG21 STK38 SUGT1 TMEM159 TMEM239 TNIP1 TP53 VAV1	8 interacting genes: ACTB ANXA1 CEP20 ERBB2 ERBB4 NCL NTAQ1 S100B
Entrez ID		6285	6282
HPRD ID		01505	04385
Ensembl ID		ENSG00000160307	ENSG00000163191
Uniprot IDs		A0A0S2Z4C5 P04271	P31949 V9HWH9
PDB IDs		1MQ1 1UWO 2H61 2M49 2PRU 3CZT 3D0Y 3D10 3HCM 4XYN 5CSF 5CSI 5CSJ 5CSN 5D7F	1V4Z 1V50 2LUC
Enriched GO Terms of Interacting Partners?
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