FNDC11 and ID2

Data Source:
BioGRID (two hybrid)

		FNDC11	ID2
Description		fibronectin type III domain containing 11	inhibitor of DNA binding 2
Image		No pdb structure
GO Annotations	Cellular Component		Euchromatin Nucleus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding	RNA Polymerase II Activating Transcription Factor Binding Protein Binding Ion Channel Binding Protein Dimerization Activity Transcription Regulator Activity Transcription Regulator Inhibitor Activity
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Lipid Metabolic Process Cell Differentiation Circadian Regulation Of Gene Expression Mammary Gland Epithelial Cell Proliferation Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of DNA-binding Transcription Factor Activity Locomotor Rhythm Regulation Of Neuron Differentiation Positive Regulation Of Blood Pressure Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Neuron Fate Commitment Negative Regulation Of Muscle Cell Differentiation Mammary Gland Alveolus Development Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Endodermal Digestive Tract Morphogenesis Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Senescence Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Neural Precursor Cell Proliferation
Pathways			NGF-stimulated transcription
Drugs
Diseases
GWAS			Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31959851 27182965) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Cognitive decline rate in late mild cognitive impairment ( 26252872) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732) IgE levels ( 22075330) Itch intensity from mosquito bite ( 28199695) Mean corpuscular volume ( 28017375) PR interval ( 29127183 30046033 32439900 31217584) Self-reported allergy ( 23817569)
Interacting Genes		44 interacting genes: AP1B1 ARL5B CALCOCO2 CCDC102B CCDC85B CDA CDCA4 CDKN1A CERCAM CINP COG6 FAM9B GOLGA2 GPBP1 HGS HMBOX1 ID2 KRT34 KRT40 KRTAP19-6 LZTS2 MAGEA12 MDFI MGAT5B MIS18A MTUS2 PDLIM7 PSMA1 RBPMS REL RNF125 SCNM1 SERTAD1 SMN1 SMN2 SORBS3 SSX2IP TRAF2 TRIM27 UBQLN2 ZBED1 ZNF48 ZNRD2 ZRANB1	53 interacting genes: ADD1 ASB4 ASCL4 C22orf39 CDK2 DYRK1A DYRK1B ELK1 ELK3 ELK4 ELOC ENKD1 FANCL FNDC11 FRS3 GATA4 GFUS HES1 IFI16 KDM1A LRIF1 MAPK1 MAPK3 MAPK8 MSC MSGN1 MYF5 MYF6 MYOD1 MYOG NEDD9 NR0B2 PAX2 PAX5 PAX8 PICK1 PPP1CA PRMT6 RB1 RBL1 RBL2 RBM48 RHOU RIN3 SREBF1 SUV39H1 SUV39H2 TCF12 TCF3 TCF4 TCHP TNS2 UNC119
Entrez ID		79025	3398
HPRD ID		14682	02664
Ensembl ID		ENSG00000125531	ENSG00000115738
Uniprot IDs		Q9BVV2	Q02363 Q53T66
PDB IDs			4AYA
Enriched GO Terms of Interacting Partners?
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