ID2 and GFUS

Data Source:
BioGRID (two hybrid)

		ID2	GFUS
Description		inhibitor of DNA binding 2	GDP-L-fucose synthase
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GO Annotations	Cellular Component	Euchromatin Nucleus Cytoplasm Cytosol Protein-containing Complex	Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding Protein Binding Ion Channel Binding Protein Dimerization Activity Transcription Regulator Activity Transcription Regulator Inhibitor Activity	Protein Binding Electron Transfer Activity GDP-4-dehydro-D-rhamnose Reductase Activity Identical Protein Binding GDP-mannose 3,5-epimerase Activity GDP-L-fucose Synthase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Lipid Metabolic Process Cell Differentiation Circadian Regulation Of Gene Expression Mammary Gland Epithelial Cell Proliferation Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of DNA-binding Transcription Factor Activity Locomotor Rhythm Regulation Of Neuron Differentiation Positive Regulation Of Blood Pressure Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Neuron Fate Commitment Negative Regulation Of Muscle Cell Differentiation Mammary Gland Alveolus Development Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Endodermal Digestive Tract Morphogenesis Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Senescence Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Neural Precursor Cell Proliferation	Leukocyte Cell-cell Adhesion Positive Regulation Of Endothelial Cell Migration GDP-mannose Metabolic Process Electron Transport Chain 'de Novo' GDP-L-fucose Biosynthetic Process Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin
Pathways		NGF-stimulated transcription	GDP-fucose biosynthesis
Drugs			NADH
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31959851 27182965) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Cognitive decline rate in late mild cognitive impairment ( 26252872) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732) IgE levels ( 22075330) Itch intensity from mosquito bite ( 28199695) Mean corpuscular volume ( 28017375) PR interval ( 29127183 30046033 32439900 31217584) Self-reported allergy ( 23817569)
Interacting Genes		53 interacting genes: ADD1 ASB4 ASCL4 C22orf39 CDK2 DYRK1A DYRK1B ELK1 ELK3 ELK4 ELOC ENKD1 FANCL FNDC11 FRS3 GATA4 GFUS HES1 IFI16 KDM1A LRIF1 MAPK1 MAPK3 MAPK8 MSC MSGN1 MYF5 MYF6 MYOD1 MYOG NEDD9 NR0B2 PAX2 PAX5 PAX8 PICK1 PPP1CA PRMT6 RB1 RBL1 RBL2 RBM48 RHOU RIN3 SREBF1 SUV39H1 SUV39H2 TCF12 TCF3 TCF4 TCHP TNS2 UNC119	4 interacting genes: ID2 NEDD4 RIOK2 UBC
Entrez ID		3398	7264
HPRD ID		02664	00654
Ensembl ID		ENSG00000115738	ENSG00000104522
Uniprot IDs		Q02363 Q53T66	A0A140VKC8 Q13630
PDB IDs		4AYA	4B8W 4B8Z 4BKP 4BL5 4E5Y
Enriched GO Terms of Interacting Partners?
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