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OTUB2 and ARRDC3
Data Source:
BioGRID
(two hybrid)
OTUB2
ARRDC3
Description
OTU deubiquitinase, ubiquitin aldehyde binding 2
arrestin domain containing 3
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Lysosome
Endosome
Early Endosome
Plasma Membrane
Molecular Function
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
NEDD8-specific Protease Activity
Ubiquitin Binding
Protein Binding
Beta-3 Adrenergic Receptor Binding
Biological Process
Protein Deubiquitination
Protein Phosphopantetheinylation
Protein K11-linked Deubiquitination
Protein K63-linked Deubiquitination
Protein K48-linked Deubiquitination
Negative Regulation Of Histone H2A K63-linked Ubiquitination
Negative Regulation Of Double-strand Break Repair
Temperature Homeostasis
Protein Transport
Negative Regulation Of Heat Generation
Skin Development
Positive Regulation Of Ubiquitin-protein Transferase Activity
Fat Pad Development
Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Negative Regulation Of Locomotion Involved In Locomotory Behavior
Negative Regulation Of Cold-induced Thermogenesis
Pathways
Ovarian tumor domain proteases
Drugs
Diseases
GWAS
Breast cancer (
29059683
25038754
)
Breast cancer (prognosis) (
23319801
)
Breast cancer (survival) (
25526632
)
Platelet distribution width (
32888494
)
Subcutaneous adipose tissue (
22589738
)
Interacting Genes
42 interacting genes:
APP
ARRDC3
CDIP1
CPSF6
DAZAP2
FAM168A
GLI2
KRT31
KRT40
LZTS2
MAGEA11
MID1
MID2
MKRN1
PHLDA2
PJA1
PLEKHB2
PMEPA1
RBCK1
REL
RFFL
RNF126
SIAH1
SPART
TP53BP2
TRAF6
TRIM2
TRIM25
TRIM26
TRIM27
TRIM39
TRIM5
TRIM54
TRIM55
TRIM63
TRIM8
TRIP6
U2AF2
UBC
UBE2N
USP21
USP28
40 interacting genes:
ADRB2
BAG3
BCL6
CCDC50
CDA
DCUN1D1
EFEMP2
EPN2
F2R
FAM90A1
HPGDS
ITCH
MAGI2
MORF4L1
NEDD4L
OPTN
OTUB2
PDCD6IP
PHF1
PRKAA2
RABGEF1
RACK1
RAD18
SMARCD1
STAM2
TNFAIP3
TOLLIP
TRIM42
UBA52
UBAC1
UBASH3A
UBE2D1
UBE2D2
UBE2E2
UBE2E3
UBQLN2
WWOX
WWP1
WWP2
ZRANB1
Entrez ID
78990
57561
HPRD ID
07620
09810
Ensembl ID
ENSG00000089723
ENSG00000113369
Uniprot IDs
Q96DC9
Q96B67
PDB IDs
1TFF
4FJV
5QIO
5QIP
5QIQ
5QIR
5QIS
5QIT
5QIU
5QIV
5QIW
5QIX
5QIY
5QIZ
4N7H
4R7V
4R7X
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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