NPHS2 and NPHS1

Data Source:
HPRD (in vivo, in vitro)

		NPHS2	NPHS1
Description		NPHS2 stomatin family member, podocin	NPHS1 adhesion molecule, nephrin
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane Protein-containing Complex Slit Diaphragm Membrane Raft Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Slit Diaphragm Cell Projection Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Myosin Binding Cell Adhesion Molecule Binding
	Biological Process	Excretion Actin Cytoskeleton Reorganization Metanephric Glomerular Visceral Epithelial Cell Development	Cell Adhesion JNK Cascade Skeletal Muscle Tissue Development Myoblast Fusion Excretion Positive Regulation Of Actin Filament Polymerization Glomerular Basement Membrane Development Protein Localization To Synapse Regulation Of Excretion Glomerular Visceral Epithelial Cell Development Cell-cell Adhesion
Pathways		Nephrin family interactions	Nephrin family interactions Nephrin family interactions
Drugs
Diseases		Nephrotic syndrome and focal segmental glomerulosclerosis	Nephrotic syndrome and focal segmental glomerulosclerosis
GWAS
Interacting Genes		4 interacting genes: CD2AP KIRREL1 KIRREL3 NPHS1	11 interacting genes: CASK CD2AP FYN IQGAP1 KIRREL1 LYN NCK1 NCK2 NPHS2 SRC YES1
Entrez ID		7827	4868
HPRD ID		05303	04094
Ensembl ID		ENSG00000116218	ENSG00000161270
Uniprot IDs		Q9NP85	O60500
PDB IDs			4ZRT
Enriched GO Terms of Interacting Partners?
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