NPHS1 and NPHS2

Data Source:
HPRD (in vivo, in vitro)

		NPHS1	NPHS2
Description		NPHS1 adhesion molecule, nephrin	NPHS2 stomatin family member, podocin
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Slit Diaphragm Cell Projection Extracellular Exosome	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane Protein-containing Complex Slit Diaphragm Membrane Raft Extracellular Exosome
	Molecular Function	Protein Binding Myosin Binding Cell Adhesion Molecule Binding	Protein Binding
	Biological Process	Cell Adhesion JNK Cascade Skeletal Muscle Tissue Development Myoblast Fusion Excretion Positive Regulation Of Actin Filament Polymerization Glomerular Basement Membrane Development Protein Localization To Synapse Regulation Of Excretion Glomerular Visceral Epithelial Cell Development Cell-cell Adhesion	Excretion Actin Cytoskeleton Reorganization Metanephric Glomerular Visceral Epithelial Cell Development
Pathways		Nephrin family interactions Nephrin family interactions	Nephrin family interactions
Drugs
Diseases		Nephrotic syndrome and focal segmental glomerulosclerosis	Nephrotic syndrome and focal segmental glomerulosclerosis
GWAS
Interacting Genes		11 interacting genes: CASK CD2AP FYN IQGAP1 KIRREL1 LYN NCK1 NCK2 NPHS2 SRC YES1	4 interacting genes: CD2AP KIRREL1 KIRREL3 NPHS1
Entrez ID		4868	7827
HPRD ID		04094	05303
Ensembl ID		ENSG00000161270	ENSG00000116218
Uniprot IDs		O60500	Q9NP85
PDB IDs		4ZRT
Enriched GO Terms of Interacting Partners?
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