ZNF165 and AHCYL1

Data Source:
BioGRID (two hybrid)

		ZNF165	AHCYL1
Description		zinc finger protein 165	adenosylhomocysteinase like 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Apical Plasma Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	RNA Binding Adenosylhomocysteinase Activity Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	MRNA Polyadenylation Protein Export From Nucleus One-carbon Metabolic Process Apoptotic Process Positive Regulation Of Sodium Ion Transport Regulation Of MRNA 3'-end Processing Regulation Of Ion Transmembrane Transporter Activity S-adenosylmethionine Cycle Angiotensin-activated Signaling Pathway Epithelial Fluid Transport Regulation Of Anion Transport Response To Calcium Ion Regulation Of Cardiac Conduction Mitochondrion-endoplasmic Reticulum Membrane Tethering
Pathways			PLC beta mediated events DAG and IP3 signaling Role of phospholipids in phagocytosis FCERI mediated Ca+2 mobilization Regulation of insulin secretion VEGFR2 mediated cell proliferation Ion homeostasis Ion homeostasis CLEC7A (Dectin-1) induces NFAT activation FCGR3A-mediated IL10 synthesis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 31451708) Fish- and plant-related diet ( 32066663) HDL cholesterol levels ( 32203549) Hepcidin/ferritin ratio ( 27846281) LDL cholesterol levels ( 32203549) Moderate to vigorous physical activity levels ( 29899525) Refractive error ( 32231278) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Squamous cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545)	Height ( 31562340)
Interacting Genes		46 interacting genes: AHCYL1 CARD10 CCDC125 CCDC130 CCDC85B CEP70 DVL2 DVL3 ELOA2 EMD EWSR1 FAM124A GOLGA6L9 GPATCH2L HOMEZ IL16 KAT7 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-12 MAB21L3 MID2 NTAQ1 PDLIM7 PICK1 PLEKHF2 PPL RNPS1 SCAND1 SUV39H1 TRIM41 ZKSCAN8 ZNF24 ZNF250 ZNF263 ZNF417 ZNF446 ZNF572 ZNF668 ZNF774 ZNF837	25 interacting genes: BID CDKN2C DACH1 GEM HBQ1 HEXIM2 HGS HSPA6 ITPR1 JOSD2 LRRK2 MEOX2 MFHAS1 PLEKHG5 PPL PRDM6 PSMD9 RNF6 SLC23A1 SOX30 SRPK1 SRPK2 SUMO2 UACA ZNF165
Entrez ID		7718	10768
HPRD ID		02903	07613
Ensembl ID		ENSG00000197279	ENSG00000168710
Uniprot IDs		P49910 Q53Z40	A0A024R0A8 O43865
PDB IDs			3MTG
Enriched GO Terms of Interacting Partners?
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