VSNL1 and TFF1

Data Source:
BioGRID (two hybrid)

		VSNL1	TFF1
Description		visinin like 1	trefoil factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane	Extracellular Region Extracellular Space
	Molecular Function	Calcium Ion Binding Protein Binding	Protein Binding Growth Factor Activity
	Biological Process	Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion	Carbohydrate Metabolic Process Signal Transduction Negative Regulation Of Cell Population Proliferation Response To Iron Ion Cell Differentiation Maintenance Of Gastrointestinal Epithelium Response To Immobilization Stress Response To Peptide Hormone
Pathways			Estrogen-dependent gene expression
Drugs			Raloxifene Afimoxifene
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Energy expenditure ( 30071075) Psychosis and Alzheimer's disease ( 22005930) Response to fenofibrate (total cholesterol levels) ( 27002377) Squamous cell lung carcinoma ( 28604730)	Blood protein levels ( 30072576 29875488) Pancreatic cancer ( 22158540)
Interacting Genes		17 interacting genes: ACTB ATXN1 C1QTNF2 CDSN CHRNA4 COL10A1 DTX2 ENDOD1 FAM131C GFI1B LITAF SPRED1 SPRED2 SPRY3 SRL TEX13B TFF1	20 interacting genes: AKT1 APC ATM BTN3A1 BTNL8 CD300LD ESR2 FCRL4 FGFR2 GKN2 MUC6 RAD51 SGTB SIGLEC8 TSG101 UBQLN1 UBQLN4 VSNL1 XRCC3 ZNF250
Entrez ID		7447	7031
HPRD ID		02890	00219
Ensembl ID		ENSG00000163032	ENSG00000160182
Uniprot IDs		P62760	P04155
PDB IDs			1HI7 1PS2 6V1D
Enriched GO Terms of Interacting Partners?
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