TRPV1 and SYT9

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		TRPV1	SYT9
Description		transient receptor potential cation channel subfamily V member 1	synaptotagmin 9
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Intrinsic Component Of Plasma Membrane Dendritic Spine Membrane Postsynaptic Membrane	Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Secretory Granule Membrane Dense Core Granule Exocytic Vesicle Hippocampal Mossy Fiber To CA3 Synapse
	Molecular Function	Transmembrane Signaling Receptor Activity Ion Channel Activity Extracellular Ligand-gated Ion Channel Activity Excitatory Extracellular Ligand-gated Ion Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding ATP Binding Calcium-release Channel Activity Phosphatidylinositol Binding Metal Ion Binding Phosphoprotein Binding	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Syntaxin Binding Clathrin Binding Identical Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Chemosensory Behavior Cellular Response To Heat Thermoception Release Of Sequestered Calcium Ion Into Cytosol Protein Homotetramerization Excitatory Postsynaptic Potential Calcium Ion Transmembrane Transport Cellular Response To Alkaloid Cellular Response To ATP Cellular Response To Acidic PH Calcium Ion Import Across Plasma Membrane Response To Capsazepine	Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Insulin Secretion Membrane Organization Cellular Response To Calcium Ion Calcium-dependent Activation Of Synaptic Vesicle Fusion
Pathways		TRP channels	Neurexins and neuroligins Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs		alpha-Linolenic acid Icosapent Aspartame Tramadol Acetaminophen Camphor Ricinoleic Acid Resiniferatoxin Capsaicin Cannabidiol Zucapsaicin Propacetamol Capsicum oleoresin Nonivamide (S)-camphor Medical Cannabis Nabiximols Cannabidivarin
Diseases
GWAS			3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Breast cancer and/or colorectal cancer ( 29698419) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Chagas cardiomyopathy in Tripanosoma cruzi seropositivity ( 24324551) Dietary fat liking ( 32516399) Familial lung cancer ( 29924316) Lead levels ( 26025379) Malaria ( 31844061) Phospholipid levels (plasma) ( 22359512) QRS duration in Tripanosoma cruzi seropositivity ( 24324551)
Interacting Genes		8 interacting genes: AKAP5 CALM1 EGFR ITCH PRKCE SNAPIN SYT9 TRPV2	10 interacting genes: CSNK1A1 DNAJC5 NRXN1 SNAP25 SYNCRIP TMBIM6 TMEM50A TRPV1 TUBB UPK1B
Entrez ID		7442	143425
HPRD ID		03648	11618
Ensembl ID		ENSG00000196689	ENSG00000170743
Uniprot IDs		Q8NER1	Q86SS6
PDB IDs		6L93
Enriched GO Terms of Interacting Partners?
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