SYT9 and TRPV1

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		SYT9	TRPV1
Description		synaptotagmin 9	transient receptor potential cation channel subfamily V member 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Secretory Granule Membrane Dense Core Granule Exocytic Vesicle Hippocampal Mossy Fiber To CA3 Synapse	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Intrinsic Component Of Plasma Membrane Dendritic Spine Membrane Postsynaptic Membrane
	Molecular Function	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Syntaxin Binding Clathrin Binding Identical Protein Binding	Transmembrane Signaling Receptor Activity Ion Channel Activity Extracellular Ligand-gated Ion Channel Activity Excitatory Extracellular Ligand-gated Ion Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding ATP Binding Calcium-release Channel Activity Phosphatidylinositol Binding Metal Ion Binding Phosphoprotein Binding
	Biological Process	Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Insulin Secretion Membrane Organization Cellular Response To Calcium Ion Calcium-dependent Activation Of Synaptic Vesicle Fusion	Cell Surface Receptor Signaling Pathway Chemosensory Behavior Cellular Response To Heat Thermoception Release Of Sequestered Calcium Ion Into Cytosol Protein Homotetramerization Excitatory Postsynaptic Potential Calcium Ion Transmembrane Transport Cellular Response To Alkaloid Cellular Response To ATP Cellular Response To Acidic PH Calcium Ion Import Across Plasma Membrane Response To Capsazepine
Pathways		Neurexins and neuroligins Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	TRP channels
Drugs			alpha-Linolenic acid Icosapent Aspartame Tramadol Acetaminophen Camphor Ricinoleic Acid Resiniferatoxin Capsaicin Cannabidiol Zucapsaicin Propacetamol Capsicum oleoresin Nonivamide (S)-camphor Medical Cannabis Nabiximols Cannabidivarin
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Breast cancer and/or colorectal cancer ( 29698419) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Chagas cardiomyopathy in Tripanosoma cruzi seropositivity ( 24324551) Dietary fat liking ( 32516399) Familial lung cancer ( 29924316) Lead levels ( 26025379) Malaria ( 31844061) Phospholipid levels (plasma) ( 22359512) QRS duration in Tripanosoma cruzi seropositivity ( 24324551)
Interacting Genes		10 interacting genes: CSNK1A1 DNAJC5 NRXN1 SNAP25 SYNCRIP TMBIM6 TMEM50A TRPV1 TUBB UPK1B	8 interacting genes: AKAP5 CALM1 EGFR ITCH PRKCE SNAPIN SYT9 TRPV2
Entrez ID		143425	7442
HPRD ID		11618	03648
Ensembl ID		ENSG00000170743	ENSG00000196689
Uniprot IDs		Q86SS6	Q8NER1
PDB IDs			6L93
Enriched GO Terms of Interacting Partners?
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