UTRN and PGM5

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		UTRN	PGM5
Description		utrophin	phosphoglucomutase 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Membrane Filopodium Growth Cone Cortical Actin Cytoskeleton Filopodium Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Postsynaptic Membrane Extracellular Exosome Contractile Ring	Stress Fiber Cytosol Adherens Junction Spot Adherens Junction Focal Adhesion Cytoplasmic Side Of Plasma Membrane Intercalated Disc Dystrophin-associated Glycoprotein Complex Z Disc Cell-substrate Junction Sarcolemma Costamere
	Molecular Function	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding Actin Filament Binding	Magnesium Ion Binding Phosphoglucomutase Activity Structural Molecule Activity
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Neuromuscular Junction Development Response To Denervation Involved In Regulation Of Muscle Adaptation Regulation Of Sodium Ion Transmembrane Transporter Activity	Carbohydrate Metabolic Process Glucose Metabolic Process Cell Adhesion Striated Muscle Tissue Development Myofibril Assembly
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Loneliness (multivariate analysis) ( 27629369) Multisite chronic pain ( 31194737) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Refractive error ( 32231278) Remission after SSRI treatment in MDD or openness ( 29559929) Response to fenofibrate (triglyceride levels) ( 27002377) Response to mepolizumab in severe asthma ( 29229094) Response to SSRI in MDD or openness ( 29559929)	Bipolar disorder ( 22925353) Metabolite levels ( 23823483)
Interacting Genes		20 interacting genes: ACTA1 ACTN2 C1QTNF9 CALM1 DAG1 DISC1 DMD DRP2 DTNA DTNB ITGB1BP1 MARCHF5 MARK2 PGM5 PTEN PTPN12 SASH1 SNTA1 SNTB1 SNTB2	2 interacting genes: DMD UTRN
Entrez ID		7402	5239
HPRD ID		00547	02990
Ensembl ID		ENSG00000152818	ENSG00000154330
Uniprot IDs		P46939 Q6LBS5	Q15124
PDB IDs		1BHD 1QAG 6M5G
Enriched GO Terms of Interacting Partners?
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