UTRN and DRP2

Data Source:
HPRD (in vitro)

		UTRN	DRP2
Description		utrophin	dystrophin related protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Membrane Filopodium Growth Cone Cortical Actin Cytoskeleton Filopodium Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Postsynaptic Membrane Extracellular Exosome Contractile Ring	Plasma Membrane Postsynaptic Density Dendrite Perikaryon Glutamatergic Synapse
	Molecular Function	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding Actin Filament Binding	Zinc Ion Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Neuromuscular Junction Development Response To Denervation Involved In Regulation Of Muscle Adaptation Regulation Of Sodium Ion Transmembrane Transporter Activity	Central Nervous System Development Synapse Organization Synaptic Signaling
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination	EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Loneliness (multivariate analysis) ( 27629369) Multisite chronic pain ( 31194737) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Refractive error ( 32231278) Remission after SSRI treatment in MDD or openness ( 29559929) Response to fenofibrate (triglyceride levels) ( 27002377) Response to mepolizumab in severe asthma ( 29229094) Response to SSRI in MDD or openness ( 29559929)
Interacting Genes		20 interacting genes: ACTA1 ACTN2 C1QTNF9 CALM1 DAG1 DISC1 DMD DRP2 DTNA DTNB ITGB1BP1 MARCHF5 MARK2 PGM5 PTEN PTPN12 SASH1 SNTA1 SNTB1 SNTB2	4 interacting genes: DAG1 DTNA PRX UTRN
Entrez ID		7402	1821
HPRD ID		00547	02083
Ensembl ID		ENSG00000152818	ENSG00000102385
Uniprot IDs		P46939 Q6LBS5	A0A024RCH3 Q13474
PDB IDs		1BHD 1QAG 6M5G
Enriched GO Terms of Interacting Partners?
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