USP1 and NMRAL1

Data Source:
BioGRID (pull down, pull down)

		USP1	NMRAL1
Description		ubiquitin specific peptidase 1	NmrA like redox sensor 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Peptidase Activity	Protein Binding Identical Protein Binding
	Biological Process	Skeletal System Development Regulation Of DNA Repair Ubiquitin-dependent Protein Catabolic Process Response To UV Protein Deubiquitination Protein Phosphopantetheinylation Monoubiquitinated Protein Deubiquitination Interstrand Cross-link Repair DNA Damage Response, Detection Of DNA Damage	Urea Cycle
Pathways		Recognition of DNA damage by PCNA-containing replication complex Fanconi Anemia Pathway	Urea cycle
Drugs			2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID
Diseases
GWAS		Crohn's disease ( 26192919 28067908) Lipid traits ( 24386095) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolic syndrome ( 31589552) Red blood cell count ( 32888494) Regular attendance at a gym or sports club ( 29970889) Serum metabolite levels (CMS) ( 31636271) Triglyceride levels ( 32203549) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)	Blood protein levels ( 29875488) Erectile dysfunction ( 30583798) Schizophrenia ( 28991256) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		15 interacting genes: DTX3 EZH2 EZR FANCD2 FANCI KLHDC2 KPNA1 NMRAL1 PCNA PHF7 TRAF6 TRIM46 UBB UBC UBE2K	4 interacting genes: FOXJ1 PCNA USP1 WDR48
Entrez ID		7398	57407
HPRD ID		04593	13678
Ensembl ID		ENSG00000162607	ENSG00000153406
Uniprot IDs		O94782	A0A384P622 Q9HBL8
PDB IDs		6DO5	2EXX 2WM3 2WMD 3DXF 3E5M
Enriched GO Terms of Interacting Partners?
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