UPK2 and ITM2C

Data Source:
BioGRID (two hybrid)

		UPK2	ITM2C
Description		uroplakin 2	integral membrane protein 2C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Apical Plasma Membrane Extracellular Exosome	Lysosome Lysosomal Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding	Amyloid-beta Binding Protein Binding ATP Binding
	Biological Process	Multicellular Organism Development Epithelial Cell Differentiation	Negative Regulation Of Neuron Projection Development Neuron Differentiation Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		33 interacting genes: ADGRG3 AMIGO1 ASGR2 ATP6AP2 BSCL2 BTNL9 C3orf52 CD74 CLDN7 CLEC17A CLEC7A FCGR1A FCGR2A FCGRT FNDC9 GPA33 HPN ITM2C KASH5 KIR2DL3 KIR3DL3 LIME1 PLP1 RNF170 SLC22A23 SMAGP STOML3 TMEM106C TMPRSS2 TNFSF11 TNFSF14 UPK1A ZNRF4	11 interacting genes: BACE1 CCL4L2 CXCL9 FNDC9 FURIN MTNR1B OLFM4 RNF7 SLC22A2 STT3A UPK2
Entrez ID		7379	81618
HPRD ID		10295	17167
Ensembl ID		ENSG00000110375	ENSG00000135916
Uniprot IDs		O00526	B8ZZM6 Q9NQX7
PDB IDs
Enriched GO Terms of Interacting Partners?
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