ITM2C and STT3A

Data Source:
HPRD (two hybrid)

		ITM2C	STT3A
Description		integral membrane protein 2C	STT3 oligosaccharyltransferase complex catalytic subunit A
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Endoplasmic Reticulum Membrane Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Oligosaccharyltransferase III Complex
	Molecular Function	Amyloid-beta Binding Protein Binding ATP Binding	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Neuron Projection Development Neuron Differentiation Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Protein N-linked Glycosylation Protein N-linked Glycosylation Via Asparagine Co-translational Protein Modification Post-translational Protein Modification
Pathways			Asparagine N-linked glycosylation Maturation of spike protein
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Breast cancer (survival) ( 25890600) Schizophrenia ( 21926974)
Interacting Genes		11 interacting genes: BACE1 CCL4L2 CXCL9 FNDC9 FURIN MTNR1B OLFM4 RNF7 SLC22A2 STT3A UPK2	6 interacting genes: CSDE1 HJURP IRAK2 ITM2C SARM1 STING1
Entrez ID		81618	3703
HPRD ID		17167	03086
Ensembl ID		ENSG00000135916	ENSG00000134910
Uniprot IDs		B8ZZM6 Q9NQX7	P46977
PDB IDs			6S7O
Enriched GO Terms of Interacting Partners?
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