UGT2B7 and CYP3A4

  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vitro, in vivo)

UGT2B7

CYP3A4

Description UDP glucuronosyltransferase family 2 member B7 cytochrome P450 family 3 subfamily A member 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875)
  • Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644)
  • Obesity-related traits ( 23251661)
  • Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Metabolic traits ( 21886157)
  • Neonatal cytokine/chemokine levels (maternal genetic effect) ( 30134952)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Sex hormone levels ( 26014426)
  • Tacrolimus trough concentration in kidney transplant patients ( 29160300)
  • Ticagrelor levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875)
Interacting Genes 2 interacting genes: CYP3A4 GABRA3 8 interacting genes: CYB5A CYP2C9 GK POR PRKACA PRKCA STUB1 UGT2B7
Entrez ID 7364 1576
HPRD ID 02508 00484
Ensembl ID ENSG00000171234 ENSG00000160868
Uniprot IDs E9PBP8 P16662 P08684 Q6GRK0
PDB IDs 2O6L 1TQN 1W0E 1W0F 1W0G 2J0D 2V0M 3NXU 3TJS 3UA1 4D6Z 4D75 4D78 4D7D 4I3Q 4I4G 4I4H 4K9T 4K9U 4K9V 4K9W 4K9X 4NY4 5A1P 5A1R 5G5J 5TE8 5VC0 5VCC 5VCD 5VCE 5VCG 6BCZ 6BD5 6BD6 6BD7 6BD8 6BDH 6BDI 6BDK 6BDM 6OO9 6OOA 6OOB
Enriched GO Terms of Interacting Partners?
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