CYP3A4 and STUB1

  • Data Source:
  • BioGRID (enzymatic study, affinity chromatography technology)

CYP3A4

STUB1

Description cytochrome P450 family 3 subfamily A member 4 STIP1 homology and U-box containing protein 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Metabolic traits ( 21886157)
  • Neonatal cytokine/chemokine levels (maternal genetic effect) ( 30134952)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Sex hormone levels ( 26014426)
  • Tacrolimus trough concentration in kidney transplant patients ( 29160300)
  • Ticagrelor levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes 8 interacting genes: CYB5A CYP2C9 GK POR PRKACA PRKCA STUB1 UGT2B7 126 interacting genes: ABL1 ACD AHR AQP2 AR ATCAY ATXN3 BACE1 BAG1 BAG5 BCR BMPR1B CASP6 CCL28 CDK4 CDKN1A CFTR CIP2A CTBP2 CTNNB1 CYP2E1 CYP3A4 DAPK1 DAXX DNAAF4 DNAJB1 E2F8 EIF5A ERBB2 ERG ERN1 ESR1 FADD FBXO2 FBXO27 FOXP3 GHR GPR37 GUCY1A1 GUCY1A2 HIF1A HSF1 HSP90AA1 HSPA1A HSPA1B HSPA4 HSPA8 HSPA9 HSPB1 INSR JOSD1 JOSD2 KHDRBS1 LRRK1 LRRK2 MAP3K11 MAP3K2 MAP3K21 MAPK3 MAPT MCF2 MFHAS1 MITF MPP1 MST1R MYOCD NOS1 NQO1 NR3C1 OLFM3 PA2G4 PFN1 PLK1 POLB POT1 POU5F1 PPARG PPP3CA PRKACA PRKCZ PRKN PRMT1 PRMT5 PSMA3 PSMD4 PTEN RAF1 RGS17 RHBDF2 RUNX2 RUSC1 S100A2 S100P SIRT6 SMAD1 SMAD2 SMAD3 SMAD4 SMG5 SMURF1 SNPH SRC TAL1 TERF1 TGFBR1 TINF2 TPD52 TRAF6 TXN2 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2L3 UBE2N UBE2Q1 UBE2V1 UBE2V2 UBE2W VCP XIAP
Entrez ID 1576 10273
HPRD ID 00484 06232
Ensembl ID ENSG00000160868 ENSG00000103266
Uniprot IDs P08684 Q6GRK0 Q9UNE7
PDB IDs 1TQN 1W0E 1W0F 1W0G 2J0D 2V0M 3NXU 3TJS 3UA1 4D6Z 4D75 4D78 4D7D 4I3Q 4I4G 4I4H 4K9T 4K9U 4K9V 4K9W 4K9X 4NY4 5A1P 5A1R 5G5J 5TE8 5VC0 5VCC 5VCD 5VCE 5VCG 6BCZ 6BD5 6BD6 6BD7 6BD8 6BDH 6BDI 6BDK 6BDM 6OO9 6OOA 6OOB 4KBQ 6EFK 6NSV
Enriched GO Terms of Interacting Partners?
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