UBE2D3 and CBLC

UBE2D3

CBLC

Description ubiquitin conjugating enzyme E2 D3 Cbl proto-oncogene C
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma and attention deficit hyperactivity disorder ( 31619474)
  • Diastolic blood pressure ( 30224653)
  • Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Apolipoprotein B levels ( 32203549)
  • Body mass index ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x age interaction ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • LDL cholesterol ( 24507774)
  • Weight ( 28552196)
Interacting Genes 224 interacting genes: AMBRA1 AMFR ANAPC11 AREL1 ARIH1 ARIH2 BARD1 BFAR BIRC2 BIRC3 BIRC7 BIRC8 BMI1 BRCA1 CADPS2 CBL CBLC CHFR CNOT4 CSNK2A1 CUL4B DBN1 DCUN1D1 DDX58 DTX1 DTX2 DTX3 DTX3L DVL2 DZIP3 EPS15 ERGIC3 ESR1 F12 FBXL12 FBXL17 FBXL2 FBXO2 FBXO25 FBXO7 FBXW11 FBXW8 FOCAD FZR1 H2AC4 H3C1 H4C1 HDAC6 HECTD1 HECW1 HECW2 HERC1 HERC2 HUWE1 IKBKG ITCH KAT2B KDM1B LRSAM1 MAEA MAP3K1 MAPT MARCHF3 MARCHF5 MARCHF7 MARCHF8 MAST1 MDM2 MDM4 MEX3B MEX3C MGRN1 MIB1 MID1 MID2 MKRN1 MKRN3 MSL1 MSL2 MUL1 MYCBP2 MYLIP NBR1 NEDD4 NEDD4L NFKB1 NFKBIA NHLRC1 NOSIP OTUB1 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 PCNA PDCD5 PELI1 PER2 PJA1 PJA2 POLL POLM PRPF19 PTEN RABGEF1 RBCK1 RBX1 RCHY1 RELA RFFL RFWD3 RING1 RLIM RMND5B RNF10 RNF103 RNF111 RNF114 RNF115 RNF122 RNF125 RNF126 RNF13 RNF130 RNF14 RNF150 RNF165 RNF166 RNF167 RNF168 RNF181 RNF185 RNF19B RNF2 RNF216 RNF220 RNF25 RNF26 RNF31 RNF38 RNF4 RNF41 RNF43 RNF5 RNF8 RNFT1 RPLP1 RSPRY1 SAT1 SH3RF1 SHOC2 SIAH1 SIAH2 SMURF1 SMURF2 SOX2 SQSTM1 ST7 STAM2 STAU1 STK25 STUB1 SYVN1 TMEM129 TOPORS TP53 TP73 TRAF6 TRAIP TRIM10 TRIM17 TRIM2 TRIM23 TRIM25 TRIM26 TRIM27 TRIM28 TRIM31 TRIM32 TRIM33 TRIM35 TRIM37 TRIM38 TRIM39 TRIM43 TRIM45 TRIM5 TRIM50 TRIM54 TRIM55 TRIM58 TRIM62 TRIM63 TRIM68 TRIM69 TRIM7 TRIM72 TRIM8 TUBA1A UBA1 UBA6 UBASH3B UBE2O UBE3A UBE3C UBE4A UBE4B UBOX5 UBR5 UBTD1 UFM1 UHRF1 USP7 UVSSA WBP2 WSB1 WWP1 WWP2 XIAP XPNPEP1 ZNRF1 ZNRF2 ZNRF4 54 interacting genes: AKT1 BAP1 BIRC2 CCND2 CDK6 CDKN2B CHFR CKM CRK EGFR EPHA2 ERBB2 FGFR4 FYN GLIS2 GRB2 ITCH LATS2 LYN MAP2K3 MDM4 MYC NACAD NF2 NFIC NSD3 OTUD6A OXA1L RAF1 SH3GL3 SHC1 SPRY2 SRC STK11 TERT TGFB1I1 TP53 TRAF4 TRIM46 TRIP6 UBC UBE2D1 UBE2D2 UBE2D3 UBE2H UBE2I UBE2K UBE2L3 UBE2L6 UBE2R2 USP2 USP21 YES1 ZAP70
Entrez ID 7323 23624
HPRD ID 04269 09765
Ensembl ID ENSG00000109332 ENSG00000142273
Uniprot IDs A0A024RDH2 D6RAH7 P61077 Q9ULV8
PDB IDs 1X23 2FUH 3L1Z 3RPG 3UGB 4BVU 4R8P 4S3O 5EGG 5IFR 6CP0 6T7F 3OP0 3VRN 3VRO 3VRP 3VRQ 3VRR
Enriched GO Terms of Interacting Partners?
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