C8A and C8G

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		C8A	C8G
Description		complement C8 alpha chain	complement C8 gamma chain
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GO Annotations	Cellular Component	Extracellular Region Membrane Attack Complex Extracellular Space Membrane Extracellular Exosome Blood Microparticle	Extracellular Region Membrane Attack Complex Extracellular Exosome Blood Microparticle
	Molecular Function	Complement Binding Protein Binding Protein-containing Complex Binding	Complement Binding Protein Binding Retinol Binding Protein-containing Complex Binding
	Biological Process	Immune Response Complement Activation Complement Activation, Alternative Pathway Complement Activation, Classical Pathway Cytolysis Regulation Of Complement Activation	Complement Activation, Alternative Pathway Complement Activation, Classical Pathway Cytolysis Regulation Of Complement Activation
Pathways		Terminal pathway of complement Regulation of Complement cascade	Terminal pathway of complement Regulation of Complement cascade
Drugs		Zinc Zinc acetate	Zinc Lauric acid Citric acid Zinc acetate
Diseases		Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency	Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
GWAS		Blood protein levels ( 28240269)	Blood protein levels ( 29875488)
Interacting Genes		9 interacting genes: C8B C8G C9 CD59 GOLT1A GPR152 MMGT1 SLC10A1 SLC7A1	2 interacting genes: C8A UBQLN2
Entrez ID		731	733
HPRD ID		00409	00407
Ensembl ID		ENSG00000157131	ENSG00000176919
Uniprot IDs		P07357	P07360
PDB IDs		2QOS 2QQH 2RD7 3OJY 6H03 6H04	1IW2 1LF7 2OVA 2OVD 2OVE 2QOS 2RD7 3OJY 6H03 6H04
Enriched GO Terms of Interacting Partners?
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