TYROBP and TREM2

  • Data Source:
  • HPRD (in vivo)

TYROBP

TREM2

Description transmembrane immune signaling adaptor TYROBP triggering receptor expressed on myeloid cells 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 23150908)
  • Alzheimer's disease (late onset) ( 28714976)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Blood protein levels ( 30072576)
  • C-reactive protein ( 22939635)
  • Family history of Alzheimer's disease ( 30617256)
  • Supraventricular ectopy ( 29618737)
Interacting Genes 15 interacting genes: CD300E CLEC5A KIR3DS1 KLRC3 KLRC4 KLRK1 NCR2 SIGLEC14 SIRPB1 SLC35B4 SYK TMEM86A TREM1 TREM2 ZAP70 10 interacting genes: APOA1 APOA2 APOB APOE CLU GH1 NRN1L SCGB2A2 TYROBP UNC5B
Entrez ID 7305 54209
HPRD ID 04996 05473
Ensembl ID ENSG00000011600 ENSG00000095970
Uniprot IDs O43914 X6RGC9 Q5TCX1 Q9NZC2
PDB IDs 2L34 2L35 4WO1 4WOL 5ELI 5UD7 5UD8 6B8O 6Z0G 6Z0H 6Z0I
Enriched GO Terms of Interacting Partners?
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