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TXNRD1 and LINC01554
Data Source:
BioGRID
(unspecified method)
TXNRD1
LINC01554
Description
thioredoxin reductase 1
long intergenic non-protein coding RNA 1554
Image
No pdb structure
GO Annotations
Cellular Component
Fibrillar Center
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Extracellular Exosome
Molecular Function
Thioredoxin-disulfide Reductase Activity
Protein Binding
Protein Disulfide Oxidoreductase Activity
Flavin Adenine Dinucleotide Binding
Biological Process
Mesoderm Formation
Selenium Compound Metabolic Process
Signal Transduction
Cell Population Proliferation
Nucleobase-containing Small Molecule Interconversion
Regulation Of Lipid Metabolic Process
Cellular Response To Oxidative Stress
Cell Redox Homeostasis
Cellular Oxidant Detoxification
Pathways
PPARA activates gene expression
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se
Detoxification of Reactive Oxygen Species
Interconversion of nucleotide di- and triphosphates
Metabolism of ingested MeSeO2H into MeSeH
Uptake and function of diphtheria toxin
TP53 Regulates Metabolic Genes
Drugs
Arsenic trioxide
NADPH
Flavin adenine dinucleotide
Spermidine
Fotemustine
Motexafin gadolinium
PX-12
Diseases
GWAS
Blood protein levels (
30072576
)
Emphysema annual change measurement in smokers (percent low attenuation area) (
31324189
)
Logical memory (delayed recall) in normal cognition (
29274321
)
Toenail selenium levels (
25343990
)
Interacting Genes
11 interacting genes:
DMRTC2
ESR1
ESR2
GLRX2
LINC01554
POU2F1
POU2F2
PPP1R16A
THRA
TXNDC17
TXNIP
141 interacting genes:
AARS1
ACADVL
ACIN1
ACTB
ACTG1
ACTN1
ACTN3
ACTR3
ALDOA
ANXA2
ANXA5
ANXA6
APEX1
ARHGAP1
ASS1
ATAD3A
ATIC
ATP5F1A
BZW2
CANX
CCT2
CCT3
CCT4
CCT6A
CCT7
CKAP4
CS
CTPS1
DDX3X
DDX46
DHX9
DNAH2
DNAJA1
DST
DYNC1H1
EDARADD
EEF1G
EEF2
EIF3A
EIF3E
EIF4A2
EIF4B
ENO1
ENO3
EPRS1
ERO1A
G3BP1
G6PD
GANAB
GAPDH
GARS1
GDI2
GPI
GTF2I
HIVEP2
HMCN1
HNRNPF
HSP90AA1
HSP90B1
HSPA1L
HSPA5
HSPA8
HSPA9
HSPD1
HYOU1
IDH1
IPO4
IPO7
IPO9
ITPR2
KARS1
KPNA1
KPNB1
KRT18
KRT7
KRT8
KRT8P3
LRPPRC
MCM7
MSN
MYO18A
NAP1L1
NAP1L4
NCBP1
NCL
NPM1
OLA1
OXCT1
PABPC1
PCBP2
PDIA3
PDIA6
PFAS
PGD
PGK1
PGM1
PHGDH
PKM
PLOD2
PMPCA
POR
PPP2R1A
PSMC1
PSMD2
PSMD7
PTBP1
RDX
RPL6
RPSA
RTCB
RTN4
SARS1
SEPTIN7
SEPTIN9
SERPINH1
SFPQ
SQSTM1
TARS1
TGFBI
THOP1
TKT
TTF2
TUBA1A
TUBA8
TUBB
TUBB2A
TUBB3
TUBB4A
TUBB4B
TUBB6
TUFM
TXNRD1
TYMP
UBA1
VCL
VCP
VIM
VPS35
WARS1
XPO1
XRCC5
Entrez ID
7296
202299
HPRD ID
03068
16896
Ensembl ID
ENSG00000198431
ENSG00000236882
Uniprot IDs
B7Z2S5
Q16881
PDB IDs
1W1C
2CFY
2J3N
2ZZ0
2ZZB
2ZZC
3QFA
3QFB
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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