TP53BP1 and PCNT

  • Data Source:
  • BioGRID (two hybrid)

TP53BP1

PCNT

Description tumor protein p53 binding protein 1 pericentrin
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Antibody level in response to infection ( 25758998)
  • Apolipoprotein A1 levels ( 32203549)
  • Cardiometabolic and hematological traits ( 27668658)
  • Eosinophil counts ( 32888494)
  • HDL cholesterol levels ( 32203549 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
  • Lung cancer in ever smokers ( 28604730)
  • Mean corpuscular volume ( 32888494)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglycerides ( 27036123)
  • Heel bone mineral density ( 30598549)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Treatment resistant depression ( 30468137)
Interacting Genes 54 interacting genes: ANKS1A ARAP1 ATM BCL6 BLM BRCA1 BRCA2 C10orf55 CCDC120 CCNB1 CDK1 CHEK1 CRB2 CREB5 DCLRE1A DCLRE1C DYNLL1 E2F1 EP300 GALNTL5 H2AX H4-16 H4C14 HGS IFI16 KAT8 KDM1A KLHDC7B LIG4 MDC1 MEOX2 NCOA3 NEK1 NFKB1 NUDT16L1 OXER1 PAXIP1 PCNT PITX1 POU6F2 RAD18 RAD50 RAD51 RBL1 RBL2 RELA SPAG9 SUMO2 TFDP1 TLX3 TP53 UBAP2 USP28 VAC14 11 interacting genes: AKAP9 CALM1 CALM2 CCP110 CEP55 DISC1 PCM1 TP53BP1 TUBG1 TUBGCP2 TUBGCP3
Entrez ID 7158 5116
HPRD ID 05569 05804
Ensembl ID ENSG00000067369 ENSG00000160299
Uniprot IDs A6NNK5 Q12888 O95613
PDB IDs 1GZH 1KZY 1XNI 2G3R 2IG0 2LVM 2MWO 2MWP 3LGF 3LGL 3LH0 4CRI 4RG2 4X34 5ECG 5J26 5KGF 5Z78 5ZCJ 6CO1 6CO2 6IU7 6IUA 6MXX 6MXY 6MXZ 6MY0 6RML 6RMM 6UPT 6VA5 6VIP
Enriched GO Terms of Interacting Partners?
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