PCNT and TUBGCP3

Data Source:
HPRD (in vivo)

		PCNT	TUBGCP3
Description		pericentrin	tubulin gamma complex associated protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Microtubule Membrane Centriolar Satellite	Equatorial Microtubule Organizing Center Gamma-tubulin Complex Cytoplasm Centrosome Centriole Spindle Polar Microtubule Cytosol Gamma-tubulin Small Complex Membrane
	Molecular Function	Protein Binding Calmodulin Binding Molecular Adaptor Activity	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Spindle Organization Signal Transduction Regulation Of G2/M Transition Of Mitotic Cell Cycle Cilium Assembly Positive Regulation Of Intracellular Protein Transport Ciliary Basal Body-plasma Membrane Docking	Mitotic Cell Cycle Microtubule Nucleation Single Fertilization Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases		Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II) Seckel syndrome
GWAS		Heel bone mineral density ( 30598549) Pre-treatment viral load in HIV-1 infection ( 31219150) Treatment resistant depression ( 30468137)	Glycated hemoglobin levels ( 20858683)
Interacting Genes		11 interacting genes: AKAP9 CALM1 CALM2 CCP110 CEP55 DISC1 PCM1 TP53BP1 TUBG1 TUBGCP2 TUBGCP3	6 interacting genes: AKAP9 DNAJB6 IMMT PCNT TUBG1 TUBG2
Entrez ID		5116	10426
HPRD ID		05804	10289
Ensembl ID		ENSG00000160299	ENSG00000126216
Uniprot IDs		O95613	A0A087WU06 B4DYP7 Q96CW5
PDB IDs			6V6B 6V6S 6X0U
Enriched GO Terms of Interacting Partners?
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