TMSB4X and TAF1D

Data Source:
BioGRID (two hybrid)

		TMSB4X	TAF1D
Description		thymosin beta 4 X-linked	TATA-box binding protein associated factor, RNA polymerase I subunit D
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Cytoskeleton Platelet Alpha Granule Lumen	Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus Cytosol Centriolar Satellite Mitotic Spindle
	Molecular Function	RNA Binding Actin Monomer Binding Protein Binding Enzyme Binding	DNA Binding Protein Binding Identical Protein Binding
	Biological Process	Platelet Degranulation Actin Filament Organization Cytoplasmic Sequestering Of NF-kappaB Regulation Of Cell Migration Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-8 Production Tumor Necrosis Factor-mediated Signaling Pathway Sequestering Of Actin Monomers Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Inflammatory Response Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Proton-transporting ATP Synthase Activity, Rotational Mechanism Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of ATP Biosynthetic Process	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Positive Regulation Of Gene Expression, Epigenetic
Pathways		Platelet degranulation	SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Asthma ( 30929738) Asthma (childhood onset) ( 30929738)
Interacting Genes		38 interacting genes: ACTA1 ACTA2 ACTB ACTG1 AKAP8L ALAS1 ANXA7 APLP1 CDKN1A COG6 FAM118B FHL3 GOLGA6L9 GRB7 HSF2BP IGSF21 ILK KRT13 KRT15 KRT31 KRT34 KRT36 KRT40 KRTAP8-1 LIMS1 PNMA1 PPP4C RAD21 RBPMS SCHIP1 SMN1 TAF1D TGM2 TK1 TRIM23 TRIM27 TRIP6 UHMK1	24 interacting genes: CEP70 DDAH2 EZH2 FAF1 FAM20C FEZ1 HAP1 HSP90AB1 IMMT ING5 ITFG1 LRIF1 MCM3AP MCPH1 NGEF NHLH2 POLB PTN RPL36AL SMARCB1 TAF1B TMSB4X UBE2D1 UBTF
Entrez ID		7114	79101
HPRD ID		02153	14679
Ensembl ID		ENSG00000205542	ENSG00000166012
Uniprot IDs		A2VCK8 P62328 Q0P5T0	A0A024R3A9 Q9H5J8
PDB IDs		1UY5 3TU5 4PL7 4PL8
Enriched GO Terms of Interacting Partners?
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