TMOD1 and ODC1

Data Source:
BioGRID (two hybrid)

		TMOD1	ODC1
Description		tropomodulin 1	ornithine decarboxylase 1
Image
GO Annotations	Cellular Component	Cytosol Cytoskeleton Striated Muscle Thin Filament Actin Filament COP9 Signalosome Membrane Myofibril Sarcomere Cortical Cytoskeleton	Cellular_component Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Tropomyosin Binding Actin Filament Binding	Ornithine Decarboxylase Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Muscle Contraction Actin Filament Organization Adult Locomotory Behavior Muscle Filament Sliding Myofibril Assembly Pointed-end Actin Filament Capping Lens Fiber Cell Development	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Response To Virus Putrescine Biosynthetic Process From Ornithine Regulation Of Protein Catabolic Process
Pathways		Striated Muscle Contraction	Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines
Drugs			Pyridoxal phosphate Spermine Putrescine Pyridoxine phosphate N-Pyridoxyl-Glycine-5-Monophosphate L-Eflornithine N(6)-(pyridoxal phosphate)-L-lysine Geneticin Eflornithine
Diseases
GWAS		Barrett's esophagus ( 27527254) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Intracranial aneurysm ( 30823506) Obesity-related traits ( 23251661) Thyroid cancer (Papillary, radiation-related) ( 20350937) Zinc levels ( 26025379)
Interacting Genes		16 interacting genes: APC BUB1 CDH1 CDKN2A DCC DLC1 FBXL17 FBXW7 MLH3 NEB ODC1 PIK3CA PRKAA2 TLR2 TMSB10 TPM3	18 interacting genes: BAAT CSNK2B GORASP2 HEMGN KAT5 MAP2K1 NANS OAZ1 OAZ2 OAZ3 RSC1A1 SSR1 STX17 TDRD7 TK1 TMOD1 TSTD2 ZNF510
Entrez ID		7111	4953
HPRD ID		01838	01324
Ensembl ID		ENSG00000136842	ENSG00000115758
Uniprot IDs		P28289	B4DXF8 P11926
PDB IDs		4PKG 4PKH 4PKI 4Z8G 4Z94	1D7K 2ON3 2OO0 4ZGY 5BWA
Enriched GO Terms of Interacting Partners?
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