TMF1 and RAB6A

Data Source:
HPRD (in vitro)

		TMF1	RAB6A
Description		TATA element modulatory factor 1	RAB6A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle
	Molecular Function	DNA Binding Protein Binding Nuclear Receptor Coactivator Activity Androgen Receptor Binding	GTPase Activity Protein Binding GTP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Acrosome Assembly Positive Regulation Of Cytokine Production Spermatid Nucleus Differentiation Negative Regulation Of Gene Expression Flagellated Sperm Motility Androgen Receptor Signaling Pathway Luteinizing Hormone Secretion Leydig Cell Differentiation Defense Response To Bacterium Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Testosterone Secretion	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Viral Process Peptidyl-cysteine Methylation Antigen Processing And Presentation Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Neutrophil Degranulation Minus-end-directed Organelle Transport Along Microtubule
Pathways		Retrograde transport at the Trans-Golgi-Network	Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Meat-related diet ( 32066663) Metabolite levels ( 23823483)	Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)
Interacting Genes		9 interacting genes: AR CMTM5 FER GFI1B ITSN2 KAT2B NR3C1 RAB6A SMARCA4	21 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TMF1
Entrez ID		7110	5870
HPRD ID		03081	01543
Ensembl ID		ENSG00000144747	ENSG00000175582
Uniprot IDs		A0A024R370 P82094 Q6PII6	A0A024R5H8 A0A024R5J5 P20340 Q53ET8
PDB IDs			1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF
Enriched GO Terms of Interacting Partners?
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