RAB6A and ERC1

Data Source:
HPRD (in vitro, two hybrid)

		RAB6A	ERC1
Description		RAB6A, member RAS oncogene family	ELKS/RAB6-interacting/CAST family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle	Golgi Membrane Cytoplasm Centrosome IkappaB Kinase Complex Ciliary Basal Body Presynaptic Membrane Synapse Cytoskeleton Of Presynaptic Active Zone
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Domain Specific Binding Myosin V Binding	Protein Binding PDZ Domain Binding Small GTPase Binding Leucine Zipper Domain Binding Cadherin Binding Structural Constituent Of Presynaptic Active Zone
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Viral Process Peptidyl-cysteine Methylation Antigen Processing And Presentation Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Neutrophil Degranulation Minus-end-directed Organelle Transport Along Microtubule	Regulation Of Transcription, DNA-templated I-kappaB Phosphorylation Neuromuscular Synaptic Transmission Multicellular Organism Development Protein Transport Retrograde Transport, Endosome To Golgi Negative Regulation Of Apoptotic Process Regulation Of Synaptic Plasticity Maintenance Of Presynaptic Active Zone Structure Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)	Attention deficit hyperactivity disorder (hyperactivity-impulsivity symptoms) ( 32595297) Body mass index ( 26426971) Forehead morphology ( 29921221) Height ( 29782485) Lumbar spine bone mineral density ( 22504420) Medial temporal lobe substructure volumes ( 32768867)
Interacting Genes		21 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SYTL5 TMF1	9 interacting genes: APP DNAJC5 ITSN2 PPFIA1 RAB6A RAB6B RIMS1 SRPK2 YWHAG
Entrez ID		5870	23085
HPRD ID		01543	06181
Ensembl ID		ENSG00000175582	ENSG00000082805
Uniprot IDs		A0A024R5H8 A0A024R5J5 P20340 Q53ET8	G8JLD3 Q8IUD2 X6RLX0
PDB IDs		1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF
Enriched GO Terms of Interacting Partners?
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