TK1 and PDE4DIP

Data Source:
BioGRID (two hybrid)

		TK1	PDE4DIP
Description		thymidine kinase 1	phosphodiesterase 4D interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril
	Molecular Function	Thymidine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Identical Protein Binding	Protein Binding Enzyme Binding Molecular Adaptor Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Phosphorylation Pyrimidine Nucleoside Salvage Thymidine Metabolic Process Protein Homotetramerization DNA Biosynthetic Process	Cellular Protein-containing Complex Assembly Regulation Of Golgi Organization
Pathways		G1/S-Specific Transcription Pyrimidine salvage
Drugs		Dithioerythritol Thymidine 5'-triphosphate
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Leukocyte telomere length ( 32109421) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)	Capecitabine sensitivity ( 22864933)
Interacting Genes		162 interacting genes: A1BG A2M AAMP ABHD4 ACTB ACTL6B ACTR1B ADAMTS10 ADD1 AGAP1 ALAS1 ALB APLP1 APP ARFGAP1 ATG16L2 ATP5F1B ATP6V1A ATXN3 BAG6 BOLA2 BOLA2B CARHSP1 CCDC115 CCDC90B CDC20 CDK1 CDK4 CDKN1A CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE6 CRIP2 CRMP1 CSAD DACT1 DALRD3 DCAF13 DDAH2 DEAF1 DMPK DOCK7 DRAP1 DUS2 DYNC1I1 DYNC2I1 DYNLT2B EEF1A1 EIF3G EIF4A2 EIF6 ERG28 EXT2 EZH2 F13A1 FAF1 FAM20C FBN3 FGB FLAD1 FST GAPDH GDF9 GDI1 GET3 GLB1 GPCPD1 HADHB HERC3 HMGXB3 HSPBAP1 IER3IP1 IGHM IMMT INPP5K INTS11 ITSN1 JADE1 JMJD1C KDM6B KIF21B KIF5A KLHL23 KLHL5 KMT2B LRIF1 MAGEA4 MAST2 MED31 METTL23 MKI67 MPP1 MPPED1 MRFAP1 MRPL20-AS1 MRPL37 MSH2 NEUROD2 NGFR NKIRAS2 NMT2 NRBP1 ODC1 PAAF1 PDE4DIP PJA1 PKM PLD3 PLXNA3 PPP4C PROC PSME1 PTPN4 PTPRK QARS1 RBBP4 RBM48 REX1BD RPA1 RPL13 RPS2 RUVBL1 RXRA SDF4 SEMA5B SEPTIN6 SETDB1 SEZ6L2 SMC5 SNX1 SP110 SULT1A3 SUMO2 SUMO3 TAF1C THOC3 TIAM2 TLE1 TMSB4X TP53 TRIM46 TRMT2A TSC2 TTC38 TUBA1A TUBB2A TUBB3 TYK2 UNC119 UPF2 USP4 WDR18 WDR73 WIZ ZBTB16 ZNF431 ZXDC	85 interacting genes: ADH1B AEN AKTIP ANKRD11 ARNT2 BYSL C1orf109 CCDC146 CCDC198 CDC5L CDKN1A CHCHD3 CLIP4 CWF19L2 EGR2 FAM161A FAM50B FAM74A4 FCHSD2 FES FHL1 GADD45G GFI1B GOLGA8EP GOLGA8F HAUS1 HOXB5 HOXC8 ITSN2 KDM1A KLC3 KLC4 KRAS KRT18 KRT31 LAMTOR3 LENG1 LIN37 LMO4 MAPRE3 MIF4GD MTUS2 MYBPC2 MYOM1 NAA10 NEFL NEK2 OSGEP PDE4D PEA15 PFDN1 PIAS4 PPP1R18 PRNP PRPF31 PYGM RTP5 SCNM1 SDCBP SH2D4A SHFL SMN1 SNCA TEAD4 TFIP11 TK1 TNIK TRAF4 TULP3 UTP14C VAC14 ZBTB24 ZBTB38 ZBTB4 ZFYVE21 ZKSCAN3 ZNF124 ZNF408 ZNF410 ZNF414 ZNF512B ZNF581 ZNF587 ZNF696 ZSCAN26
Entrez ID		7083	9659
HPRD ID		01771	10482
Ensembl ID		ENSG00000167900	ENSG00000178104
Uniprot IDs		A0A384MDV9 K7ES52 P04183	A0A075B749 A0A087WYE4 Q5VU43
PDB IDs		1W4R 1XBT 2ORV 2WVJ
Enriched GO Terms of Interacting Partners?
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