TK1 and MRFAP1

Data Source:
BioGRID (two hybrid)

		TK1	MRFAP1
Description		thymidine kinase 1	Morf4 family associated protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Thymidine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Identical Protein Binding	Protein Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Phosphorylation Pyrimidine Nucleoside Salvage Thymidine Metabolic Process Protein Homotetramerization DNA Biosynthetic Process
Pathways		G1/S-Specific Transcription Pyrimidine salvage
Drugs		Dithioerythritol Thymidine 5'-triphosphate
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Leukocyte telomere length ( 32109421) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		162 interacting genes: A1BG A2M AAMP ABHD4 ACTB ACTL6B ACTR1B ADAMTS10 ADD1 AGAP1 ALAS1 ALB APLP1 APP ARFGAP1 ATG16L2 ATP5F1B ATP6V1A ATXN3 BAG6 BOLA2 BOLA2B CARHSP1 CCDC115 CCDC90B CDC20 CDK1 CDK4 CDKN1A CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE6 CRIP2 CRMP1 CSAD DACT1 DALRD3 DCAF13 DDAH2 DEAF1 DMPK DOCK7 DRAP1 DUS2 DYNC1I1 DYNC2I1 DYNLT2B EEF1A1 EIF3G EIF4A2 EIF6 ERG28 EXT2 EZH2 F13A1 FAF1 FAM20C FBN3 FGB FLAD1 FST GAPDH GDF9 GDI1 GET3 GLB1 GPCPD1 HADHB HERC3 HMGXB3 HSPBAP1 IER3IP1 IGHM IMMT INPP5K INTS11 ITSN1 JADE1 JMJD1C KDM6B KIF21B KIF5A KLHL23 KLHL5 KMT2B LRIF1 MAGEA4 MAST2 MED31 METTL23 MKI67 MPP1 MPPED1 MRFAP1 MRPL20-AS1 MRPL37 MSH2 NEUROD2 NGFR NKIRAS2 NMT2 NRBP1 ODC1 PAAF1 PDE4DIP PJA1 PKM PLD3 PLXNA3 PPP4C PROC PSME1 PTPN4 PTPRK QARS1 RBBP4 RBM48 REX1BD RPA1 RPL13 RPS2 RUVBL1 RXRA SDF4 SEMA5B SEPTIN6 SETDB1 SEZ6L2 SMC5 SNX1 SP110 SULT1A3 SUMO2 SUMO3 TAF1C THOC3 TIAM2 TLE1 TMSB4X TP53 TRIM46 TRMT2A TSC2 TTC38 TUBA1A TUBB2A TUBB3 TYK2 UNC119 UPF2 USP4 WDR18 WDR73 WIZ ZBTB16 ZNF431 ZXDC	41 interacting genes: ABI1 ABI2 ABI3 BRK1 C14orf93 C3orf62 C8orf33 CAVIN3 CCDC146 DCDC2 DNAJB5 DPY30 FCHSD2 GOLGA8F GOLGA8G HTT KIFC3 MAP1LC3B MORF4L1 MORF4L2 MRFAP1L1 MTIF3 PAM16 PCBD2 PRAP1 PRKAA2 SDCBP SH2D4A SMU1 SUV39H2 TEX11 TK1 TPM2 TRIM47 TXN TXN2 UBTD1 UQCC2 WASHC1 ZDHHC17 ZNF655
Entrez ID		7083	93621
HPRD ID		01771	17589
Ensembl ID		ENSG00000167900	ENSG00000179010
Uniprot IDs		A0A384MDV9 K7ES52 P04183	A0A087WTY9 B3KQA0 Q9Y605
PDB IDs		1W4R 1XBT 2ORV 2WVJ
Enriched GO Terms of Interacting Partners?
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