TIMP1 and EEF1B2

Data Source:
HPRD (two hybrid)

		TIMP1	EEF1B2
Description		TIMP metallopeptidase inhibitor 1	eukaryotic translation elongation factor 1 beta 2
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GO Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Platelet Alpha Granule Lumen Extracellular Exosome	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex
	Molecular Function	Protease Binding Cytokine Activity Protein Binding Growth Factor Activity Metalloendopeptidase Inhibitor Activity Zinc Ion Binding Peptidase Inhibitor Activity	Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Cell Activation Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Platelet Degranulation Aging Positive Regulation Of Cell Population Proliferation Response To Hormone Response To Organic Substance Negative Regulation Of Endopeptidase Activity Cytokine-mediated Signaling Pathway Extracellular Matrix Disassembly Response To Cytokine Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Response To Peptide Hormone Post-translational Protein Modification Cellular Protein Metabolic Process Negative Regulation Of Membrane Protein Ectodomain Proteolysis Cartilage Development Cellular Response To UV-A Negative Regulation Of Trophoblast Cell Migration Negative Regulation Of Metallopeptidase Activity Regulation Of Integrin-mediated Signaling Pathway	Translational Elongation Regulation Of Catalytic Activity
Pathways		Platelet degranulation Activation of Matrix Metalloproteinases Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Interleukin-10 signaling Interleukin-4 and Interleukin-13 signaling Post-translational protein phosphorylation	Eukaryotic Translation Elongation
Drugs
Diseases
GWAS			Body mass index ( 26426971)
Interacting Genes		8 interacting genes: CD63 ECH1 EEF1B2 MMP1 MMP2 MMP3 MYOC RECQL5	13 interacting genes: AARS1 APP CSNK2A1 CSNK2A2 DRD3 EEF1G HARS1 SPRYD4 TIMP1 TPT1 ULK2 VHL WBP2
Entrez ID		7076	1933
HPRD ID		02371	02804
Ensembl ID		ENSG00000102265	ENSG00000114942
Uniprot IDs		B4DJK3 P01033 Q6FGX5	A0A024R3W7 P24534
PDB IDs		1D2B 1LQN 1OO9 1UEA 2J0T 3MA2 3V96 6MAV 6N9D	1B64 5DQS
Enriched GO Terms of Interacting Partners?
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