TGFB1 and TGFB2

  • Data Source:
  • HPRD (in vivo)

TGFB1

TGFB2

Description transforming growth factor beta 1 transforming growth factor beta 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181 30542056)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Bone mineral density (hip) ( 30172743)
  • Central corneal thickness ( 32528159 29760442)
  • Chronic obstructive pulmonary disease ( 28166215 30804561)
  • Chronic obstructive pulmonary disease (severe) ( 24621683)
  • Diastolic blood pressure ( 30224653)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Emphysema imaging phenotypes ( 26030696)
  • FEV1 ( 30804560)
  • Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)
  • Heel bone mineral density ( 30598549)
  • Height ( 20881960 25282103 25429064 31562340)
  • Hip circumference adjusted for BMI ( 25673412)
  • Hip minimal joint space width ( 27701424)
  • Intraocular pressure ( 29617998)
  • Local histogram emphysema pattern ( 25006744)
  • Lung function (FEV1/FVC) ( 30804560)
  • Lung function (FVC) ( 30804560)
  • Peak expiratory flow ( 30804560)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Pulmonary function ( 21946350)
  • Refractive error ( 32231278)
  • Rosacea symptom severity ( 29771307)
  • Systolic blood pressure ( 30578418)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes 95 interacting genes: ACVRL1 ADAMTSL4 AGR3 ANGPTL4 APC APP AURKA AXIN2 BCAS3 BCL10 BGN BLID BMP2 BMP3 BMPR1A BUB1 CATSPER1 CCDC33 CCL3 CCL5 CCN2 CDKN2A COL2A1 CST6 CYSRT1 DAXX DCN DIRAS3 DLC1 DPT EGFR EIF3I ENG ERBB2 FBXW7 FCHO1 FCN1 FKBP1A FMOD FNTA GREB1 HOXA1 HOXC6 ITGAV ITGB6 ITGB8 KLK5 KLK7 KLK9 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP4-11 LAMTOR5 LCE1A LCE1C LCE1D LCE2B LCE2C LCE3A LCE3B LCE3D LPXN LTBP1 LTBP3 LTBP4 MCC MEOX2 MLH3 MMP2 MTA3 NSD3 P4HB PDGFRL PDLIM2 POU4F2 PRSS50 PSMC3IP PZP RAPGEF3 SCGB3A1 SDC2 SNAI1 SPARC ST14 TGFB2 TGFBR1 TGFBR2 TGFBR3 THBS1 THRSP TLR2 VASN VTN YWHAE 15 interacting genes: APP BMP2 CCN2 DCN ENG FMOD LTBP3 PZP TGFB1 TGFB3 TGFBR1 TGFBR2 TGFBR3 VASN VTN
Entrez ID 7040 7042
HPRD ID 01821 01828
Ensembl ID ENSG00000105329 ENSG00000092969
Uniprot IDs A0A499FJK2 P01137 P61812 Q59EG9
PDB IDs 1KLA 1KLC 1KLD 3KFD 4KV5 5FFO 5VQP 6OM2 6P7J 1TFG 2TGI 4KXZ 5TX4 5TY4 6I9J
Enriched GO Terms of Interacting Partners?
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